INVESTIGATION OF THE EFFECT OF CHITOSAN AND SAL VADORA PERSICA ON BLOOD LIPIDS IN THE WISTAR RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

EZ ALDINI ARDAKANI F.; AKHAVAN KARBASI M.H.; VAHIDI ALI REZA; MIR JALILI N.; ESLAM POUR N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2007 | Volume:16 | Issue:1 Page(s): 40-47

Download Full-Text

Persian Verion

View:

1,066

Download:

Cites:

Information Journal Paper

Title

INVESTIGATION OF THE EFFECT OF CHITOSAN AND SAL VADORA PERSICA ON BLOOD LIPIDS IN THE WISTAR RAT

Author(s)

Keywords

CHITOSANQ3

SALVADORA PERSICAQ2

BLOOD LIPIDSQ3

HYPERCHOLESTEROLEMIAQ2

RATSQ2

Abstract

Introduction: HYPERCHOLESTEROLEMIA is a metabolic disorder that ultimately results in arterial sclerosis and complications like hypertension and coronary arterial diseases. Various drugs have been used for the treatment of this condition and many studies are underway for introducing new drugs. CHITOSAN and SALVADORA PERSICA are two such drugs. CHITOSAN is produced by deactivation of chitin which is present mainly in the exoskeleton of crustaceans. The aim of this invitro study was to study the effects of these two drugs on blood lipid levels.Methods: In this Interventional Laboratory Trial, 30 mature vistar RATS weighing 200-250 grams were selected and after a period of two weeks in order to allow them to adapt to their surroundings, they were allotted randomly to 6 groups. The RATS were then fed for a period of 15 days with normal or fatty diet, with or without the drugs. CHITOSAN in pure powder form and persica in the form of hydro alcoholic SALVADORA PERSICA stem extract were added to the diet of the respective study groups. At the end of this period, blood samples were taken in order to measure cholesterol, triglyceride, HDL and LDL levels. Data was analyzed statistically using SPSS software program and Scheffe, ANOVA and Descriptive statistical tests. Results: Both CHITOSAN and persica decreased cholesterol and LDL levels in the groups ingesting fatty diet (P< 0.05) and the mean decrease was not statistically different for the two drugs. (P>0.05). The two drugs had no effect on triglyceride and HDL levels. (P > 0.05) Both CHITOSAN and persica had no effect on blood lipid levels of subjects on normal diet whose cholesterol levels were normal (P > 0.05).Conclusion: Persica and CHITOSAN have similar effects on reduction of cholesterol and LDL levels in cases of HYPERCHOLESTEROLEMIA, but have no effect on triglyceride and HDL levels.

Cites

EFFECT OF AERIAL PARTS EXTRACT OF ECHINOPHORA PLATYLOBA.L ON LIVER AND KIDNEY FUNCTION TESTS IN OBESE HYPERCHOLESTEROLAEMIA RATS

References

No record.

Cite

APA: Copy

EZ ALDINI ARDAKANI, F., AKHAVAN KARBASI, M.H., VAHIDI, ALI REZA, MIR JALILI, N., & ESLAM POUR, N.. (2007). INVESTIGATION OF THE EFFECT OF CHITOSAN AND SAL VADORA PERSICA ON BLOOD LIPIDS IN THE WISTAR RAT. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 16(1), 40-47. SID. https://sid.ir/paper/36221/en

Vancouver: Copy

EZ ALDINI ARDAKANI F., AKHAVAN KARBASI M.H., VAHIDI ALI REZA, MIR JALILI N., ESLAM POUR N.. INVESTIGATION OF THE EFFECT OF CHITOSAN AND SAL VADORA PERSICA ON BLOOD LIPIDS IN THE WISTAR RAT. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;16(1):40-47. Available from: https://sid.ir/paper/36221/en

IEEE: Copy

F. EZ ALDINI ARDAKANI, M.H. AKHAVAN KARBASI, ALI REZA VAHIDI, N. MIR JALILI, and N. ESLAM POUR, “INVESTIGATION OF THE EFFECT OF CHITOSAN AND SAL VADORA PERSICA ON BLOOD LIPIDS IN THE WISTAR RAT,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 1, pp. 40–47, 2007, [Online]. Available: https://sid.ir/paper/36221/en

Related Journal Papers