COMPARISON OF EFFICACY OF ORAL FLUCONAZOLE WITH INTRAMUSCULAR GLUCANTIME IN PATIENTS WITH ACUTE CUTANEOUS LEISHMANIASIS

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FAMILI SOROUR ALZAMAN; PEZESHKPOUR F.A.Z.; SEPEHR V.; VAHEDIAN MOHAMMAD

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Journal: Iranian Journal of Dermatology Year:2005 | Volume:8 | Issue:2 Page(s): 97-100

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Title

COMPARISON OF EFFICACY OF ORAL FLUCONAZOLE WITH INTRAMUSCULAR GLUCANTIME IN PATIENTS WITH ACUTE CUTANEOUS LEISHMANIASIS

Author(s)

FAMILI SOROUR ALZAMAN | PEZESHKPOUR F.A.Z. | SEPEHR V. | VAHEDIAN MOHAMMAD | Issue Writer Certificate

Keywords

CUTANEOUS LEISHMANIASISQ3

FLUCONAZOLEQ4

GLUCANTIMEQ3

Abstract

Background: CUTANEOUS LEISHMANIASIS is an important skin parasitic disease. Ideal treatment is not found yet and seeking for proper drugs continues. Objective: Comparison of the efficacy of FLUCONAZOLE with systemic GLUCANTIME in patients with acute cutaneous leishmanisis in Ghaem Hospital in Mashhad in 2002 Patients and Methods: During one year of study, all patients with cutaneous leishmaniasis were divided to two groups. Thirty-one patients were treated with oral FLUCONAZOLE (100 mg twice a day) for 6 weeks and patients treated with 29 were intramuscular GLUCANTIME (20 mgSb/kg) for 21 days. Both groups were evaluated 3 and 6 weeks after onset of treatment. "T" test and chi-square test were used for statistical analyses and P<0.05 was considered as significant. Results: Six weeks after begining .of treatment, clinical cure, improvement and failure were observed in 4(12.9%) , 11 (35.5%) and 16(51.5%) of patients treated with FLUCONAZOLE, respectively. These figures were 11(37.9%), 10(34.6%)and 8(21.5%) of patients treated with GLUCANTIME, respectively (P>0.05). Conclusion: It seems that efficacy of FLUCONAZOLE in acute CUTANEOUS LEISHMANIASIS is lower than GLUCANTIME. A larger clinical trial is recommended.

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APA: Copy

FAMILI, SOROUR ALZAMAN, PEZESHKPOUR, F.A.Z., SEPEHR, V., & VAHEDIAN, MOHAMMAD. (2005). COMPARISON OF EFFICACY OF ORAL FLUCONAZOLE WITH INTRAMUSCULAR GLUCANTIME IN PATIENTS WITH ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY, 8(2), 97-100. SID. https://sid.ir/paper/362394/en

Vancouver: Copy

FAMILI SOROUR ALZAMAN, PEZESHKPOUR F.A.Z., SEPEHR V., VAHEDIAN MOHAMMAD. COMPARISON OF EFFICACY OF ORAL FLUCONAZOLE WITH INTRAMUSCULAR GLUCANTIME IN PATIENTS WITH ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2005;8(2):97-100. Available from: https://sid.ir/paper/362394/en

IEEE: Copy

SOROUR ALZAMAN FAMILI, F.A.Z. PEZESHKPOUR, V. SEPEHR, and MOHAMMAD VAHEDIAN, “COMPARISON OF EFFICACY OF ORAL FLUCONAZOLE WITH INTRAMUSCULAR GLUCANTIME IN PATIENTS WITH ACUTE CUTANEOUS LEISHMANIASIS,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 8, no. 2, pp. 97–100, 2005, [Online]. Available: https://sid.ir/paper/362394/en

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