Evaluation of antioxidant, anti-cancer and anti-inflammatory characteristics of bio-synthesized silver nanoparticles produced by waste extract of Rheum ribes L.

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Naeimi Zahra; NEAMATI ALI; HOMAYOUNI TABRIZI MASOUD

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Journal: Feyz Medical Sciences Journal Year:2019 | Volume:23 | Issue:3 Page(s): 241-252

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Title

Evaluation of antioxidant, anti-cancer and anti-inflammatory characteristics of bio-synthesized silver nanoparticles produced by waste extract of Rheum ribes L.

Author(s)

Naeimi Zahra | NEAMATI ALI | HOMAYOUNI TABRIZI MASOUD | Issue Writer Certificate

Keywords

Rheum ribes LQ1

Silver nanoparticlesQ2

AntioxidantQ2

CancerQ2

Anti-inflammationQ1

Abstract

Background: This study was designed to evaluate the Antioxidant, Anti-inflammation and anti-Cancer potency of Silver nanoparticles produced by waste Rheum ribes L. extract. Materials and Methods: in this study, 10 gr of dried Rheum ribes L powder after 3 hours dissolving at 37° C was filtered and applied for Silver nanoparticles preparation. Particle size, X-ray diffractometer (XRD), Fourier transform infrared radiometer (FT-IR) and transmission electron microscope (TEM) methods were used to measurement the properties of Silver nanoparticles. The 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium (MTT) method accompanied by 2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) compounds were used to evaluate the cytotoxicity and Antioxidant capacity of the nanoparticles. Results: The size of the produced Silver nanoparticles was 28 nm with a uniform distribution and spherical appearance. The effective Antioxidant dose for the ABTS and DPPH compounds was 200 μ g/ml, and the obtained IC50 on HDF, Huvec, and MCF-7 cells for 24, 48 and 72 hours treatment were 30, 25, 12; 13. 2, 11, 10; and 10, 9 and 8 μ g/ml, respectively. Conclusion: The Silver nanoparticles produced by waste Rheum ribes L. extract can have potential for use as a therapeutic strategy against Cancer.

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APA: Copy

Naeimi, Zahra, NEAMATI, ALI, & HOMAYOUNI TABRIZI, MASOUD. (2019). Evaluation of antioxidant, anti-cancer and anti-inflammatory characteristics of bio-synthesized silver nanoparticles produced by waste extract of Rheum ribes L.. FEYZ, 23(3 ), 241-252. SID. https://sid.ir/paper/365247/en

Vancouver: Copy

Naeimi Zahra, NEAMATI ALI, HOMAYOUNI TABRIZI MASOUD. Evaluation of antioxidant, anti-cancer and anti-inflammatory characteristics of bio-synthesized silver nanoparticles produced by waste extract of Rheum ribes L.. FEYZ[Internet]. 2019;23(3 ):241-252. Available from: https://sid.ir/paper/365247/en

IEEE: Copy

Zahra Naeimi, ALI NEAMATI, and MASOUD HOMAYOUNI TABRIZI, “Evaluation of antioxidant, anti-cancer and anti-inflammatory characteristics of bio-synthesized silver nanoparticles produced by waste extract of Rheum ribes L.,” FEYZ, vol. 23, no. 3 , pp. 241–252, 2019, [Online]. Available: https://sid.ir/paper/365247/en

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