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Information Journal Paper

Title

DUAL EFFECT OF AEROBIC EXERCISE AND GNRH AGONISTS AT THE SAME TIME, ON ESTRADIOL SERUM LEVELSANDGONADOTROPINS (LH,LH/FSH) IN GIRLS WITH CENTRAL PRECOCIOUS PUBERTY

Pages

  899-912

Abstract

 Introduction: PRECOCIOUS PUBERTYin girls refers to onset of puberty before age 8. The purpose of this study therefore was the study of the effect of AEROBIC TRAINING and the use of GnRH agonists on ESTRADIOL serum levelsand Gonadotropins in girls with central PRECOCIOUS PUBERTY.Methods: Twenty- five girls with central PRECOCIOUS PUBERTY (aged 7.44±0.34 years) participated in this study. Subjects randomly were divided in to the healthy control group (Without PRECOCIOUS PUBERTY) (n=10) and three experimental groups (drug group) n=10 aerobic exercise and (drug groups) n=8 and aerobic exercise group (n=7). In the experimental group, aerobic program prolonged for 12 weeks 3 days a week 20-60 min a day with 40-80% of Maximum heart rate and additionally GnRH agonists was used as medicine. The ESTRADIOL serum levelsand Gonadotropins were measured before, after, and after a follow-up program, respectively. BMI of subjects was measured to assess the effect of the aerobic exercises.Results: Data analysis showed that the AEROBIC TRAINING led to decreased significantly ESTRADIOL serum levelsand Gonadotropins in the experimental group (aerobic exercise and aerobic exercise+drug groups) (P≤0/05) The control group had no significant change in the index. BMI had no significant change in the drug group (P=0/06).Conclusions: Considering to the results of this study it could demonstrate that AEROBIC TRAINING and GnRH agonists at the same time can lead to decrease the ESTRADIOL serum level sandimprove the Gonadotropins in PRECOCIOUS PUBERTY girls. AEROBIC TRAINING can also decrease the BMI in girls with central PRECOCIOUS PUBERTY.

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    APA: Copy

    HEIDARIANPOUR, ALI, RAZAVI, ZAHRA, & SEIF, MASOOMEH. (2017). DUAL EFFECT OF AEROBIC EXERCISE AND GNRH AGONISTS AT THE SAME TIME, ON ESTRADIOL SERUM LEVELSANDGONADOTROPINS (LH,LH/FSH) IN GIRLS WITH CENTRAL PRECOCIOUS PUBERTY. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 24(11), 899-912. SID. https://sid.ir/paper/36580/en

    Vancouver: Copy

    HEIDARIANPOUR ALI, RAZAVI ZAHRA, SEIF MASOOMEH. DUAL EFFECT OF AEROBIC EXERCISE AND GNRH AGONISTS AT THE SAME TIME, ON ESTRADIOL SERUM LEVELSANDGONADOTROPINS (LH,LH/FSH) IN GIRLS WITH CENTRAL PRECOCIOUS PUBERTY. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;24(11):899-912. Available from: https://sid.ir/paper/36580/en

    IEEE: Copy

    ALI HEIDARIANPOUR, ZAHRA RAZAVI, and MASOOMEH SEIF, “DUAL EFFECT OF AEROBIC EXERCISE AND GNRH AGONISTS AT THE SAME TIME, ON ESTRADIOL SERUM LEVELSANDGONADOTROPINS (LH,LH/FSH) IN GIRLS WITH CENTRAL PRECOCIOUS PUBERTY,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 11, pp. 899–912, 2017, [Online]. Available: https://sid.ir/paper/36580/en

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