Prevalence of Cleft Lip and Cleft Palate in Iran: A Systematic Review and Meta-Analysis

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HASELI AREZOO; Hajimirzaie Saeideh; BAGHERI LEILA; SADEGHIAN AFSANEH; AHMADNIA ELAHE

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:28 | Issue:168 Page(s): 185-192

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Title

Prevalence of Cleft Lip and Cleft Palate in Iran: A Systematic Review and Meta-Analysis

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Keywords

cleft palateQ2

cleft lipQ2

meta-analysisQ1

IranQ2

Abstract

Background and purpose: cleft lip and cleft palate are the most common congenital defects in the jaw and face. These defects can make serious problems, such as facial deformity, nutritional problems, respiratory problems, and difficulties with social interaction. Awareness of the incidence of these defects in the community is important. In a systematic review and meta-analysis we aimed at investigating the prevalence of cleft lip and cleft palate in Iran. Materials and methods An advanced search was conducted in all credible databases to access relevant articles using related keywords until February 1, 2018. After removing the duplicate, irrelevant, and poor quality papers, 17 articles were included. Data were analyzed applying random effects model in RevMan5. 3 software. Results Total number of samples in selected articles was 1, 077, 537 neonates. Prevalence of oral cleft, both cleft lip and cleft palate, cleft lip, and cleft palate was 1. 24 (CI 95%; 1. 10-1. 38), 0. 88 (CI 95%; 0. 70-1. 06), 0. 34 (CI 95%; 0. 28-0. 40), and 0. 35 (CI 95%; 0. 27-0. 43) in 1000 live births. The prevalence of this disorder was found to be higher in males (1. 82 vs. 1. 09). Conclusion The overall prevalence of cleft lip and cleft palate in this study was lower than that in other countries in the Middle East and Asia. But its prevalence varies in different parts of Iran, therefore, it is necessary to investigate the risk factors in high risk areas and making appropriate plans to reduce the rate of cleft lip and cleft palate.

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APA: Copy

HASELI, AREZOO, Hajimirzaie, Saeideh, BAGHERI, LEILA, SADEGHIAN, AFSANEH, & AHMADNIA, ELAHE. (2019). Prevalence of Cleft Lip and Cleft Palate in Iran: A Systematic Review and Meta-Analysis. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(168 ), 185-192. SID. https://sid.ir/paper/367105/en

Vancouver: Copy

HASELI AREZOO, Hajimirzaie Saeideh, BAGHERI LEILA, SADEGHIAN AFSANEH, AHMADNIA ELAHE. Prevalence of Cleft Lip and Cleft Palate in Iran: A Systematic Review and Meta-Analysis. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;28(168 ):185-192. Available from: https://sid.ir/paper/367105/en

IEEE: Copy

AREZOO HASELI, Saeideh Hajimirzaie, LEILA BAGHERI, AFSANEH SADEGHIAN, and ELAHE AHMADNIA, “Prevalence of Cleft Lip and Cleft Palate in Iran: A Systematic Review and Meta-Analysis,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 168 , pp. 185–192, 2019, [Online]. Available: https://sid.ir/paper/367105/en

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