Effect of creatine supplementation on creatine kinase and lactate dehydrogenase enzymes following a severe muscle contraction in female athletes: A clinical trial study

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SEDAGHAT MAHSA; RASHIDI MOHAMMAD

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Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:21 | Issue:1 (69) Page(s): 1-6

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Title

Effect of creatine supplementation on creatine kinase and lactate dehydrogenase enzymes following a severe muscle contraction in female athletes: A clinical trial study

Author(s)

SEDAGHAT MAHSA | RASHIDI MOHAMMAD | Issue Writer Certificate

Keywords

Creatine supplementQ1

Creatine kinaseQ2

Lactate dehydrogenaseQ3

Severe muscle contractionQ1

AthleteQ2

Abstract

Background and Objective: Creatine is one of the most important and commonly used supplements Athletes, although the molecular mechanisms of creatine and its side effects are less understood. The high level of the ceratin kinase enzyme and Lactate dehydrogenase enzymes are considered to be a sign of cell damage. This study was done to determine the effect of creatine monohydrate supplementation on Creatine kinase (CK) and Lactate dehydrogenase (LDH) enzymes following a Severe muscle contraction in female Athletes. Methods: In this double-blind clinical trial study, 30 female Athletes were randomly divided into intervention (Creatine supplementation 0. 3 grams per body weight for 4 times duing 7 days and control (placebo, starch powder) groups. Blood sample was collected before supplementation (pre-test) and 24 hours after Cunningham exercise test (post-test) to measuring CK and LDH in each subject. Results: After intervention, the level of CK (323± 63 IU/L) and LDH (119± 13 IU/L) in intervention group had no significant difference in compared to control group (CK: 328± 44 IU/L and LDH: 122± 14 IU/L). Conclusion: The usage of a 7-day course of Creatine supplement did not significantly change the CK and LDH levels following a Severe muscle contraction in female Athletes.

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APA: Copy

SEDAGHAT, MAHSA, & RASHIDI, MOHAMMAD. (2019). Effect of creatine supplementation on creatine kinase and lactate dehydrogenase enzymes following a severe muscle contraction in female athletes: A clinical trial study. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 21(1 (69) ), 1-6. SID. https://sid.ir/paper/367129/en

Vancouver: Copy

SEDAGHAT MAHSA, RASHIDI MOHAMMAD. Effect of creatine supplementation on creatine kinase and lactate dehydrogenase enzymes following a severe muscle contraction in female athletes: A clinical trial study. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;21(1 (69) ):1-6. Available from: https://sid.ir/paper/367129/en

IEEE: Copy

MAHSA SEDAGHAT, and MOHAMMAD RASHIDI, “Effect of creatine supplementation on creatine kinase and lactate dehydrogenase enzymes following a severe muscle contraction in female athletes: A clinical trial study,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 1 (69) , pp. 1–6, 2019, [Online]. Available: https://sid.ir/paper/367129/en

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