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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

ACANTHAMOEBA KERATITIS

Pages

  372-386

Keywords

Abstract

ACANTHAMOEBA KERATITIS (AK) is a serious, potentially sight-threatening corneal infection caused by a pathogenic free-living amoeba. Contact lens wear is the major risk factor in its etiology. This article will review previous studies on the parasitology, epidemiology, pathogenesis, clinical presentations, diagnosis and therapeutic options. This article review previous studies up to 2004 indexed in Medline with the key words: "ACANTHAMOEBA" and "keratitis", Articles with original, clinical, evidence-based and remarkable findings were selected. Data from about 30 articles were extracted. The first cases of AK were reported more than 30 years ago. Its incidence has gradually increased due to the widespread use of contact lenses. Different approaches have been developed to improve diagnosis. Various medications including aromatic diamidines, cationic antiseptics, aminoglycosides, and imidazole derivatives have been proposed for treatment of AK. The medical treatment protocol at Labbafmejad Center, is also introduced. Finally, different surgical modalities which should be considered in case of medically non-responsive AK are discussed. These include epithelial debridement, cryotherapy, lamellar keratectomy and finally penetrating keratoplasty. Although treatment of AK is difficult and time-consuming, early diagnosis and initiation of proper management has a vital role in final visual prognosis and globe integrity.

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    APA: Copy

    KARIMIAN, F.. (2004). ACANTHAMOEBA KERATITIS. BINA, 9(4 (36)), 372-386. SID. https://sid.ir/paper/368170/en

    Vancouver: Copy

    KARIMIAN F.. ACANTHAMOEBA KERATITIS. BINA[Internet]. 2004;9(4 (36)):372-386. Available from: https://sid.ir/paper/368170/en

    IEEE: Copy

    F. KARIMIAN, “ACANTHAMOEBA KERATITIS,” BINA, vol. 9, no. 4 (36), pp. 372–386, 2004, [Online]. Available: https://sid.ir/paper/368170/en

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