EFFECTS OF HYDROALCHOHOLIC EXTRACT OF TURMERIC (CURCUMA LONGA) RHIZOME ON THE PERIPHERAL AND VISCERAL PAIN IN MICE

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JADIDI MAJID; SAMENI HAMID REZA; MIRBEYGI ZEYNAB; JAFARI MARYAM; TAHERIAN ABBAS ALI

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Journal: Koomesh Year:2016 | Volume:17 | Issue:3 (59) Page(s): 692-700

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Title

EFFECTS OF HYDROALCHOHOLIC EXTRACT OF TURMERIC (CURCUMA LONGA) RHIZOME ON THE PERIPHERAL AND VISCERAL PAIN IN MICE

Author(s)

Keywords

CURCUMA LONGAQ2

CURCUMINQ1

PERIPHERAL PAINQ1

VISCERAL PAINQ2

MICEQ2

Abstract

Introduction: Previously it has been shown that CURCUMA LONGA (CL) has anti-inflammatory, antioxidant, antiviral, antifungal, antitumor, and antiniceceptive activity in neuropathic injury, when it is administered systemically, although the mechanisms that mediate these effects are not clear. The aim of present study was to determine the peripheral and visceral antinoceceptive effects of hydroalchoholic extract of CL on peripheral and visceral neuropathic pain in MICE.Materials and methods: This study was conducted using 160 young adult male albino MICE (25-30 g.) in 20 groups (n=8). CL (100, 200, and 500 mg/Kg IP), vehicle (VEH), and (Saline) were injected interaperitonealy 30 min before the pain evaluation tests. Acute and chronic pains were assessed by host plate, tail flick and formaline tests models and VISCERAL PAIN was assessed by writhing test.Results: Results indicated that CL has analgesic effects on neuropathic pain (p<0.05) than the control group and the higher dose of CL was more effective (p<0.001).Conclusion: The above findings showed that CL has modulatory effects on peripheral and VISCERAL PAINs.

Cites

ANTINOCICEPTIVE EFFECTS OF AQEOUS EXTRACT LAUNAEA ACANTHODES GUM IN MICE

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APA: Copy

JADIDI, MAJID, SAMENI, HAMID REZA, MIRBEYGI, ZEYNAB, JAFARI, MARYAM, & TAHERIAN, ABBAS ALI. (2016). EFFECTS OF HYDROALCHOHOLIC EXTRACT OF TURMERIC (CURCUMA LONGA) RHIZOME ON THE PERIPHERAL AND VISCERAL PAIN IN MICE. KOOMESH, 17(3 (59)), 692-700. SID. https://sid.ir/paper/36884/en

Vancouver: Copy

JADIDI MAJID, SAMENI HAMID REZA, MIRBEYGI ZEYNAB, JAFARI MARYAM, TAHERIAN ABBAS ALI. EFFECTS OF HYDROALCHOHOLIC EXTRACT OF TURMERIC (CURCUMA LONGA) RHIZOME ON THE PERIPHERAL AND VISCERAL PAIN IN MICE. KOOMESH[Internet]. 2016;17(3 (59)):692-700. Available from: https://sid.ir/paper/36884/en

IEEE: Copy

MAJID JADIDI, HAMID REZA SAMENI, ZEYNAB MIRBEYGI, MARYAM JAFARI, and ABBAS ALI TAHERIAN, “EFFECTS OF HYDROALCHOHOLIC EXTRACT OF TURMERIC (CURCUMA LONGA) RHIZOME ON THE PERIPHERAL AND VISCERAL PAIN IN MICE,” KOOMESH, vol. 17, no. 3 (59), pp. 692–700, 2016, [Online]. Available: https://sid.ir/paper/36884/en

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