FORMULATION AND CONTROL OF LORATADINE TABLET

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FARID J.; KARBASSI A.; NEMATI A.

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Journal: PHARMACEUTICAL SCIENCES Year:2001 | Volume:- | Issue:4 Page(s): 63-69

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Information Journal Paper

Title

FORMULATION AND CONTROL OF LORATADINE TABLET

Author(s)

FARID J. | KARBASSI A. | NEMATI A. | Issue Writer Certificate

Keywords

ANTIHISTAMINESQ3

LORATADINEQ3

H1 RECEPTORES ANTAGONISTSQ3

Abstract

Loratadine is a potent competitive antagonist of H1receptors which attaches to the peripheral H1 receptors selectively and also to the H1receptors of brain with less affinity, therefore there is almost no central nervous system side effects such as sedation.Loratadine tablets is administered one tablet each day ill the reliep of the symptoms of allergic seasonal rhinitis and idiopathic chronic urticaria.Different formulations containing 10 mg LORATADINE were prepared using wet and dry granulation methods. In wet granulation, water, starch paste and aqueous solution of PVP were used as granulating liquid. This study showed that wet granulation method using PVP aqueous solution as binder was the proper method, and the produced tablets had good physicochemical properties which were comparable with Claritin.

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APA: Copy

FARID, J., KARBASSI, A., & NEMATI, A.. (2001). FORMULATION AND CONTROL OF LORATADINE TABLET. PHARMACEUTICAL SCIENCES, -(4), 63-69. SID. https://sid.ir/paper/371308/en

Vancouver: Copy

FARID J., KARBASSI A., NEMATI A.. FORMULATION AND CONTROL OF LORATADINE TABLET. PHARMACEUTICAL SCIENCES[Internet]. 2001;-(4):63-69. Available from: https://sid.ir/paper/371308/en

IEEE: Copy

J. FARID, A. KARBASSI, and A. NEMATI, “FORMULATION AND CONTROL OF LORATADINE TABLET,” PHARMACEUTICAL SCIENCES, vol. -, no. 4, pp. 63–69, 2001, [Online]. Available: https://sid.ir/paper/371308/en

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