Relationship of maternal vitamin D level with premature rupture of fetal membranes

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Farzipour Shahla; JALILVAND FARANAK; AMANI FIROUZ; KAZEMI MASOOMEH; Nikjou roya; SHAHBAZZADEGAN SAMIRA

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Paper Information

Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2020 | Volume:23 | Issue:1 Page(s): 33-39

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Information Journal Paper

Title

Relationship of maternal vitamin D level with premature rupture of fetal membranes

Author(s)

Keywords

Fetal MembranesQ1

Pregnant WomenQ1

Premature rupture of membranesQ2

Vitamin DQ1

Abstract

Introduction: Premature rupture of membranes (PROM) is not only a major medical problem but also a social and economic problem. According to the results of some studies, Vitamin D deficiency during pregnancy and labor may play a role in Premature rupture of membranes by mechanism of inflammation in the placenta. Considering to the high prevalence of Vitamin D deficiency in pregnancy and lack of knowledge about of the determinants of Premature rupture of membranes, this study was performed with aim to investigate the relationship between maternal Vitamin D levels with Premature rupture of membranes. Methods: This case-control study was performed on 200 Pregnant Women with gestational age of 28-41 weeks who referred to Ardabil Alavi Hospital in 2018. 100 Pregnant Women with Premature rupture of membranes were selected as the case group and 100 Pregnant Women without rupture of membranes as the control group. Blood samples were taken from both groups to measure serum levels of 25-Hydroxy Vitamin D. Demographic information, laboratory data, history and type of maternal delivery were collected. Data was analyzed by SPSS software (version 20) and Chi-Square and T-tests. P<0/05 was considered statistically significant. Results: Serum level of Vitamin D in the case group was 22/73 ± 11/87 nanomoles per liter and in the control group was 25/16 ± 12/48 nanomoles per liter; the difference between two groups was not statistically significant (p=0/09). Conclusion: There was no association between maternal Vitamin D levels and Premature rupture of membranes. Further research with a larger number of samples and complete control of the intervention agents is needed to investigate the relationship between maternal Vitamin D levels and the occurrence of Premature rupture of membranes.

Cites

Evaluation of the relationship between maternal serum vitamin D level with premature amniotic sac rupture in pregnant women referred to Asalian Hospital in Khorramabad 2019-2020

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APA: Copy

Farzipour, Shahla, JALILVAND, FARANAK, AMANI, FIROUZ, KAZEMI, MASOOMEH, Nikjou, roya, & SHAHBAZZADEGAN, SAMIRA. (2020). Relationship of maternal vitamin D level with premature rupture of fetal membranes. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 23(1 ), 33-39. SID. https://sid.ir/paper/372059/en

Vancouver: Copy

Farzipour Shahla, JALILVAND FARANAK, AMANI FIROUZ, KAZEMI MASOOMEH, Nikjou roya, SHAHBAZZADEGAN SAMIRA. Relationship of maternal vitamin D level with premature rupture of fetal membranes. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2020;23(1 ):33-39. Available from: https://sid.ir/paper/372059/en

IEEE: Copy

Shahla Farzipour, FARANAK JALILVAND, FIROUZ AMANI, MASOOMEH KAZEMI, roya Nikjou, and SAMIRA SHAHBAZZADEGAN, “Relationship of maternal vitamin D level with premature rupture of fetal membranes,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 23, no. 1 , pp. 33–39, 2020, [Online]. Available: https://sid.ir/paper/372059/en

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