ASSOCIATION BETWEEN ESTROGEN AND PROGESTERONE RECEPTORS GENE POLYMORPHISMS WITH PROSTATE CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ONSORY KHADIJEH; MOUSAVI MONA; Haji Mehdi Nouri Zahra; VAHABI BARZI NASTARAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Koomesh Year:2016 | Volume:17 | Issue:2 (58) Page(s): 455-463

Download Full-Text

Persian Verion

View:

1,464

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION BETWEEN ESTROGEN AND PROGESTERONE RECEPTORS GENE POLYMORPHISMS WITH PROSTATE CANCER

Author(s)

ONSORY KHADIJEH | MOUSAVI MONA | Haji Mehdi Nouri Zahra | VAHABI BARZI NASTARAN | Issue Writer Certificate

Keywords

ESTROGEN RECEPTORQ3

PROGESTERONE RECEPTORQ3

GENE POLYMORPHISMQ2

PROSTATE CANCERQ2

Abstract

Introduction: PROSTATE CANCER, the most prevalent cancer among men, is a steroid hormone receptor-dependent cancer. Mutations in ESTROGEN RECEPTORs (ERα and ERβ) and PROGESTERONE RECEPTOR (PR) may cause steroid hormones to be involved as initiators or promoters in prostate carcinogenesis. The purpose of this study was to determine the association and frequency of incidence of the polymorphisms in the intron1 of ERa, exon 5 of ERb and intron 7 of PR in the risk of PROSTATE CANCER.Materials and methods: PROSTATE CANCER patients admitted to the Department of Urology, Postgraduate Institute of Medical Science and Research (PGIMER), Chandigarh, India (n=100) and an equal number of matching controls visiting same center underwent PCR-RFLP analysis for ERs and PR genes.Results: In the present case -control study, the results show that those patients with the genotype ERa (-/-) had significantly higher risk for PROSTATE CANCER (OR, 2.70; 95% CI, 1.08-6.70, P= 0.03). But There was no association between the Rr genotype of ERb (OR, 1.65; 95% CI, 0.52–5.23, P=0.21) and A1/A2 genotype of PR (OR, 1.90; 95% CI, 0.70-5.15; P=0.204) with the risk for PROSTATE CANCER.Conclusion: It seems that in the studied population there was an increased risk of PROSTATE CANCER among patients carrying ERα (-/-), but not with other genotypes of ERβ and PR genes.

Cites

EFFECTS OF DIETARY CONJUGATED LINOLEIC ACID ON OXIDATION MARKERS AND ANTIOXIDANT DEFENSES IN RATS WITH COLORECTAL CANCER

References

No record.

Cite

APA: Copy

ONSORY, KHADIJEH, MOUSAVI, MONA, Haji Mehdi Nouri, Zahra, & VAHABI BARZI, NASTARAN. (2016). ASSOCIATION BETWEEN ESTROGEN AND PROGESTERONE RECEPTORS GENE POLYMORPHISMS WITH PROSTATE CANCER. KOOMESH, 17(2 (58)), 455-463. SID. https://sid.ir/paper/37518/en

Vancouver: Copy

ONSORY KHADIJEH, MOUSAVI MONA, Haji Mehdi Nouri Zahra, VAHABI BARZI NASTARAN. ASSOCIATION BETWEEN ESTROGEN AND PROGESTERONE RECEPTORS GENE POLYMORPHISMS WITH PROSTATE CANCER. KOOMESH[Internet]. 2016;17(2 (58)):455-463. Available from: https://sid.ir/paper/37518/en

IEEE: Copy

KHADIJEH ONSORY, MONA MOUSAVI, Zahra Haji Mehdi Nouri, and NASTARAN VAHABI BARZI, “ASSOCIATION BETWEEN ESTROGEN AND PROGESTERONE RECEPTORS GENE POLYMORPHISMS WITH PROSTATE CANCER,” KOOMESH, vol. 17, no. 2 (58), pp. 455–463, 2016, [Online]. Available: https://sid.ir/paper/37518/en

Related Journal Papers