The Effect of 8 Weeks of Resistance Training on Changes in IL4, IL17 and Muscle Strength in Women with Multiple Sclerosis

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Shahidi Rad Mahbobe; ASKARI ROYA; Hosseini Kakhk Seyyed Alireza

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Journal: Journal of Sport Biosciences Year:2020 | Volume:11 | Issue:4 Page(s): 365-377

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Title

The Effect of 8 Weeks of Resistance Training on Changes in IL4, IL17 and Muscle Strength in Women with Multiple Sclerosis

Author(s)

Shahidi Rad Mahbobe | ASKARI ROYA | Hosseini Kakhk Seyyed Alireza | Issue Writer Certificate

Keywords

interleukin 17 and 4Q1

muscle strengthQ2

resistance trainingQ1

women with MSQ2

Abstract

Health professionals believe in the effective role of training in improving the health of MS patients. The present study investigated changes in serum IL4 and 17, as well as muscle strength changes after 8 weeks of regular resistance training in women with MS in Mashhad city. The present study was applied with pretest-posttest design. 22 women with multiple sclerosis in the age range of 25 to 40 years old and with disability (EDSS=4) were purposively assigned to experimental and control groups. The experimental group performed the training for 8 weeks, 3 sessions per week with 40-60% 1RM intensity and the control group did not participate in any regular physical activity. Before and after the training, anthropometric tests (using caliper, tape measure and level), upper and lower limb strength (with 1RM test in chest and leg presses) and blood sampling were used to measure the levels of interleukin 17 and 4. Oneway ANOVA was used for potential differences in the groups and paired t test was used to examine the within-group changes using SPSS software version 18. Statistical analysis showed that the muscle strength of the subjects in the experimental group was significantly higher in both upper and lower parts of the trunk than the control group (P=0. 001, P=0. 0001). Interleukin 4 showed a significant increase in the experimental group compared with the control group (P=0. 002), but interleukin 17 did not differ between the two groups. It seems that women with multiple sclerosis can use regular resistance training with moderate intensity to improve their immune system's efficiency and enhance their level of strength.

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APA: Copy

Shahidi Rad, Mahbobe, ASKARI, ROYA, & Hosseini Kakhk, Seyyed Alireza. (2020). The Effect of 8 Weeks of Resistance Training on Changes in IL4, IL17 and Muscle Strength in Women with Multiple Sclerosis. SPORT BIOSCIENCES (HARAKAT), 11(4 ), 365-377. SID. https://sid.ir/paper/375304/en

Vancouver: Copy

Shahidi Rad Mahbobe, ASKARI ROYA, Hosseini Kakhk Seyyed Alireza. The Effect of 8 Weeks of Resistance Training on Changes in IL4, IL17 and Muscle Strength in Women with Multiple Sclerosis. SPORT BIOSCIENCES (HARAKAT)[Internet]. 2020;11(4 ):365-377. Available from: https://sid.ir/paper/375304/en

IEEE: Copy

Mahbobe Shahidi Rad, ROYA ASKARI, and Seyyed Alireza Hosseini Kakhk, “The Effect of 8 Weeks of Resistance Training on Changes in IL4, IL17 and Muscle Strength in Women with Multiple Sclerosis,” SPORT BIOSCIENCES (HARAKAT), vol. 11, no. 4 , pp. 365–377, 2020, [Online]. Available: https://sid.ir/paper/375304/en

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