COMPARING HEMODYNAMIC CHANGES DURING ENDOSCOPIC SINUS SURGERY: REMIFENTANIL/ISOFLURAN VERSUS REMIFENTANIL/PROPOFOL

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SADEGHI SEYED MOHAMMAD; SEYEDMEHDI SEYED AHMAD; NARIMANI ZAMANABADI MAHNAZ; SADEGHI SEYED ABBAS

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2011 | Volume:68 | Issue:12 Page(s): 732-736

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Title

COMPARING HEMODYNAMIC CHANGES DURING ENDOSCOPIC SINUS SURGERY: REMIFENTANIL/ISOFLURAN VERSUS REMIFENTANIL/PROPOFOL

Author(s)

SADEGHI SEYED MOHAMMAD | SEYEDMEHDI SEYED AHMAD | NARIMANI ZAMANABADI MAHNAZ | SADEGHI SEYED ABBAS | Issue Writer Certificate

Keywords

ENDOSCOPIC SINUS SURGERYQ2

REMIFENTANILQ3

ISOFLURANEQ2

PROPOFOLQ3

BLOOD LOSSQ2

HEMODYNAMIC STATUSQ3

Abstract

Background: Sinus surgeries are usually associated with bleeding, thus can result in hemodynamic instability. This study investigated the hemodynamic changes induced by REMIFENTANIL plus ISOFLURANE administration in comparison with PROPOFOL plus REMIFENTANIL in patients undergoing sinus surgery.Methods: In this randomized clinical trial study, 96 patients were divided into two groups of ISOFLURANE (1.2 MAC) plus REMIFENTANIL (44 patients, group A) and PROPOFOL (100 mg/kg/min) plus REMIFENTANIL (52 patients, group B). Twenty-two patients in group A and 23 in group B were male. The REMIFENTANIL dosage (0.1 mg/kg/min) was equal in both groups and all received 500 ml isotonic solution during the operation too. Premedications and anesthetic inductions of both groups were similar. The variables included age, BMI, BLOOD LOSS during surgery, systolic and diastolic blood pressures, pulse rate and mean arterial blood pressure.Results: The mean age, BMI, amount of BLOOD LOSS, mean systolic (30 minutes before and after the intervention) and diastolic blood pressures (60 minutes before and after the intervention), pulse rate (30 and 60 minutes before and after the intervention), mean arterial blood pressure (60 minutes before and after the intervention) were similar in both groups. The average mean arterial blood pressure, 30 minutes after the intervention (p=0.027) and the mean diastolic blood pressure, 30 minutes after the intervention (p=0.011) in the case group had statistically significant differences with the controls.Conclusion: Based on this study, the combination of ISOFLURANE plus REMIFENTANIL could better maintain the hemodynamic stability during sinus surgeries.

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APA: Copy

SADEGHI, SEYED MOHAMMAD, SEYEDMEHDI, SEYED AHMAD, NARIMANI ZAMANABADI, MAHNAZ, & SADEGHI, SEYED ABBAS. (2011). COMPARING HEMODYNAMIC CHANGES DURING ENDOSCOPIC SINUS SURGERY: REMIFENTANIL/ISOFLURAN VERSUS REMIFENTANIL/PROPOFOL. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 68(12), 732-736. SID. https://sid.ir/paper/38172/en

Vancouver: Copy

SADEGHI SEYED MOHAMMAD, SEYEDMEHDI SEYED AHMAD, NARIMANI ZAMANABADI MAHNAZ, SADEGHI SEYED ABBAS. COMPARING HEMODYNAMIC CHANGES DURING ENDOSCOPIC SINUS SURGERY: REMIFENTANIL/ISOFLURAN VERSUS REMIFENTANIL/PROPOFOL. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2011;68(12):732-736. Available from: https://sid.ir/paper/38172/en

IEEE: Copy

SEYED MOHAMMAD SADEGHI, SEYED AHMAD SEYEDMEHDI, MAHNAZ NARIMANI ZAMANABADI, and SEYED ABBAS SADEGHI, “COMPARING HEMODYNAMIC CHANGES DURING ENDOSCOPIC SINUS SURGERY: REMIFENTANIL/ISOFLURAN VERSUS REMIFENTANIL/PROPOFOL,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 68, no. 12, pp. 732–736, 2011, [Online]. Available: https://sid.ir/paper/38172/en

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