The Effect of Intestinal Microbiota Metabolites on HT29 Cell line by Using MTT Method in Patients with Colorectal Cancer

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

gahani shrafat Somayeh; ghasemian safaei Hajie; azimi rad Masoumeh; ahmadi amili Hadi; moghim Sharare

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medical Council of Iran Year:2019 | Volume:37 | Issue:2 Page(s): 110-116

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

768

Download:

Cites:

Information Journal Paper

Title

The Effect of Intestinal Microbiota Metabolites on HT29 Cell line by Using MTT Method in Patients with Colorectal Cancer

Author(s)

Keywords

MicrobiotaQ1

Colorectal cancerQ2

HT29 Cell LineQ1

Abstract

Background: Colorectal cancer is one of the most common malignant tumors, Human guts harbor abundant microbes that adjust many aspects of host physiology. Increasing studies show that gut Microbiota plays a significant role in the incidence and expansion of CRC, as a result of virulence factors, bacterial metabolites, or inflammatory pathways. Materials and Methods: In this study, viability of HT29 cells, treated by different time of Microbiota metabolits (3, 6, 12, 18h), was assessed by MTT assay respectively. Results: Treated cells with Microbiota metabolits showed increased viability and proliferation, in time-dependent analysis by MTT assay. Conclusion: Considering that microbial metabolits is able to induce proliferation and increase cell viability, it seems microbial metabolites imbalance or dysbiosis in the gut due to the dietary or environmental changes or lifestyle risk factors may cause Colorectal cancer.

Cites

No record.

References

No record.

Cite

APA: Copy

gahani shrafat, Somayeh, ghasemian safaei, Hajie, azimi rad, Masoumeh, ahmadi amili, Hadi, & moghim, Sharare. (2019). The Effect of Intestinal Microbiota Metabolites on HT29 Cell line by Using MTT Method in Patients with Colorectal Cancer. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 37(2 ), 110-116. SID. https://sid.ir/paper/384691/en

Vancouver: Copy

gahani shrafat Somayeh, ghasemian safaei Hajie, azimi rad Masoumeh, ahmadi amili Hadi, moghim Sharare. The Effect of Intestinal Microbiota Metabolites on HT29 Cell line by Using MTT Method in Patients with Colorectal Cancer. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2019;37(2 ):110-116. Available from: https://sid.ir/paper/384691/en

IEEE: Copy

Somayeh gahani shrafat, Hajie ghasemian safaei, Masoumeh azimi rad, Hadi ahmadi amili, and Sharare moghim, “The Effect of Intestinal Microbiota Metabolites on HT29 Cell line by Using MTT Method in Patients with Colorectal Cancer,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 37, no. 2 , pp. 110–116, 2019, [Online]. Available: https://sid.ir/paper/384691/en

Related Journal Papers