EFFECTIVENESS OF COMBINATION THERAPY WITH HONEY IN H.PYLORI ERADICATION IN PEDIATRICS MEDICAL CENTRE

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KHODADAD A.; KHATAMI GH.R.; KARAMI H.; HATMI Z.N.

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Journal: Tehran University Medical Journal Year:2006 | Volume:64 | Issue:3 Page(s): 78-87

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Title

EFFECTIVENESS OF COMBINATION THERAPY WITH HONEY IN H.PYLORI ERADICATION IN PEDIATRICS MEDICAL CENTRE

Author(s)

KHODADAD A. | KHATAMI GH.R. | KARAMI H. | HATMI Z.N. | Issue Writer Certificate

Keywords

HELICOBACTER PYLORIQ3

PEPTIC DISEASEQ3

CLINICAL TRIALQ3

Abstract

Background: There are several million new cases of PEPTIC DISEASE annually. The disease has a various range of presentations. Gram negative HELICOBACTER PYLORI bacilli are considered as an etiologic factor in this disease. Goal of treatment in PEPTIC DISEASE is eradication of the HELICOBACTER PYLORI (HP).Combination therapy has been implemented in the treatment of this disease. Different modalities have been recommended up to now. In order to lower adverse effects, cost and drug resistance, researchers have introduced a new combination therapy in which honeyis substituted for metronidazole.Methods: A step II of CLINICAL TRIAL was designed. The sample size was 15 children.Diagnosis of HP infection was confirmed with histopathology. Treatment regimen consisted of omeprazole, amoxicillin, bismuth and honey. After a 3-4 week follow- up, eradication was evaluated.Results: 15 children completed the follow- up period. Mean age of patients was 9.4 years. Treatment effectiveness was 80 percent. Conclusion: Combination therapy with 3 drugs along with honey has significant effectiveness on HP eradication.

Cites

COMPARISON OF CIPROFLOXACIN-BASED TRIPLE THERAPY WITH CONVENTIONAL TRIPLE REGIMEN FOR HELICOBACTER PYLORI ERADICATION IN CHILDREN

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APA: Copy

KHODADAD, A., KHATAMI, GH.R., KARAMI, H., & HATMI, Z.N.. (2006). EFFECTIVENESS OF COMBINATION THERAPY WITH HONEY IN H.PYLORI ERADICATION IN PEDIATRICS MEDICAL CENTRE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 64(3), 78-87. SID. https://sid.ir/paper/38550/en

Vancouver: Copy

KHODADAD A., KHATAMI GH.R., KARAMI H., HATMI Z.N.. EFFECTIVENESS OF COMBINATION THERAPY WITH HONEY IN H.PYLORI ERADICATION IN PEDIATRICS MEDICAL CENTRE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2006;64(3):78-87. Available from: https://sid.ir/paper/38550/en

IEEE: Copy

A. KHODADAD, GH.R. KHATAMI, H. KARAMI, and Z.N. HATMI, “EFFECTIVENESS OF COMBINATION THERAPY WITH HONEY IN H.PYLORI ERADICATION IN PEDIATRICS MEDICAL CENTRE,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 64, no. 3, pp. 78–87, 2006, [Online]. Available: https://sid.ir/paper/38550/en

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