Effect of Resistance Training on Serum Levels of Adipolin and Insulin Resistance in Obese Women (Running title: Adipolin and resistance training)

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REZAEIAN NAJMEH; RAVASI ALI ASGHAR; SOORI RAHMAN; Akbarnezhad ali; Mirshafiey Seyyed Abbas; Towfighi Farzane

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Journal: Journal of Sport Biosciences Year:2020 | Volume:12 | Issue:1 Page(s): 1-16

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Title

Effect of Resistance Training on Serum Levels of Adipolin and Insulin Resistance in Obese Women (Running title: Adipolin and resistance training)

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Keywords

Resistance TrainingQ2

AdipolinQ1

Insulin ResistanceQ2

Obese WomenQ2

Abstract

Adipolin (CTRP12), is a novel anti-inflammatory adipokine mostly synthases and expresses in adipose tissue. Adipolin improves Insulin sensitivity and decreases circulating glucose levels. This study investigated effect of Resistance Training on Adipolin levels and Insulin Resistance index (HOMA-IR) in Obese Women. 20 sedentary postmenopausal Obese Women (BMI>30Kg/m2, aged 50-65 years) randomly assigned in to experimental (n=12) and control (n=8) groups. Subjects in experimental group participated in 12 weeks of Resistance Training (3 sets of 8-12 repetitions at 40-60% of one maximal repetition), 15-45 minutes per session and three sessions per week. Levels of Adipolin, insulin and fasting glucose and anthropometric indices measured before and 48 hours after last training session. Statistical analysis was done by Kolmogorov-smirnov, paired and independent t-test and Pearson correlation and P<0. 05 considered significant. Serum levels of Adipolin did not significantly changed following 12 weeks of Resistance Training; however, insulin levels (P=0. 032) and HOMA-IR (P=0. 031) decreased significantly. Furthermore, between groups changes of HOMA-IR (P=0. 021) and waist hip ratio (P=0. 002) were significant. According to Pearson correlation, no correlation existed between pre training and post training changes of Adipolin levels and those of blood factors assessed and anthropometric indices (P>0. 05). Therefore, Resistance Training is one of treatment procedure to improve insulin sensitivity in sedentary postmenopausal Obese Women. However, more studied is necessary to identify molecular mechanism mediated by Adipolin.

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APA: Copy

REZAEIAN, NAJMEH, RAVASI, ALI ASGHAR, SOORI, RAHMAN, Akbarnezhad, ali, Mirshafiey, Seyyed Abbas, & Towfighi, Farzane. (2020). Effect of Resistance Training on Serum Levels of Adipolin and Insulin Resistance in Obese Women (Running title: Adipolin and resistance training). SPORT BIOSCIENCES (HARAKAT), 12(1 ), 1-16. SID. https://sid.ir/paper/386881/en

Vancouver: Copy

REZAEIAN NAJMEH, RAVASI ALI ASGHAR, SOORI RAHMAN, Akbarnezhad ali, Mirshafiey Seyyed Abbas, Towfighi Farzane. Effect of Resistance Training on Serum Levels of Adipolin and Insulin Resistance in Obese Women (Running title: Adipolin and resistance training). SPORT BIOSCIENCES (HARAKAT)[Internet]. 2020;12(1 ):1-16. Available from: https://sid.ir/paper/386881/en

IEEE: Copy

NAJMEH REZAEIAN, ALI ASGHAR RAVASI, RAHMAN SOORI, ali Akbarnezhad, Seyyed Abbas Mirshafiey, and Farzane Towfighi, “Effect of Resistance Training on Serum Levels of Adipolin and Insulin Resistance in Obese Women (Running title: Adipolin and resistance training),” SPORT BIOSCIENCES (HARAKAT), vol. 12, no. 1 , pp. 1–16, 2020, [Online]. Available: https://sid.ir/paper/386881/en

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