RESPONSE TO HEPATITIS B VACCINE IN HIV-INFECTED PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AFRASIABIAN SH.; HAJI BAGHERI K.; YOUSEFINEZHAD V.; ESMAEILNASAB N.; SEYFI SH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Armaghane Danesh Year:2007 | Volume:12 | Issue:2 (46) Page(s): 11-17

Download Full-Text

Persian Verion

View:

1,212

Download:

Cites:

Information Journal Paper

Title

RESPONSE TO HEPATITIS B VACCINE IN HIV-INFECTED PATIENTS

Author(s)

Keywords

HEPATITIS B VACCINEQ3

HIV/AIDS PATIENTSQ3

CD4+ T LYMPHOCYTESQ3

Abstract

Introduction & Objective: The risk of developing chronic hepatitis B virus (HBV) is 5% in general population but can reach up to 20% in HIV patients. The response rate to HBV vaccine in HIV infected patients is 23.8-56 percent. The aim of this study was to evaluate response of HIV-infected patients to 20 μg dose of recombinant HBV vaccine.Materials & Methods: In this quasi experimental study, 51 subjects, sampled through census, were HIV patients who had HBsAg negative test in HIV/AIDS counseling and care center. Patients were vaccinated with 20 μg of recombinant HBV vaccine, IM at intervals of 0, 1 and 6 months. Response to the vaccine was checked 2 months after the last injection. Data were analyzed with SPSS software, using descriptive statistics and nonparametric tests.Results: The mean age of the patients was 33.68±8.37 years. Two patients were female (3.9%) and 49 patients were male (96.1%). Mean of hepatitis B antibody level was 47.55±71.58 mIU/ml. The levels of antibody in different patients were as follow: 31 patients (60.8%) <10 mIU/ml and 20 patients (39.2%)> 10 mIU/ml. There was no significant correlation between antibody levels and CD4+ cell count (correlation coefficient = -0.191). Conclusion: Response to hepatitis B vaccination is low in HIV infected patients. Conventional dose of HBV vaccine is not enough to get protective immunity. Therefore, two-fold dose of vaccine dose, repeat of conventional dose or increasing of interval administration of HEPATITIS B VACCINE should be considered in future studies.

Cites

No record.

References

THE RESPONSE TO HEPATITIS B VIRUS VACCINE IN HIV-INFECTED PATIENTS (HIV/AIDS COUNSELLING AND CARE CENTER IN KERMANSHAH)

Cite

APA: Copy

AFRASIABIAN, SH., HAJI BAGHERI, K., YOUSEFINEZHAD, V., ESMAEILNASAB, N., & SEYFI, SH.. (2007). RESPONSE TO HEPATITIS B VACCINE IN HIV-INFECTED PATIENTS. ARMAGHAN DANESH, 12(2 (46)), 11-17. SID. https://sid.ir/paper/388262/en

Vancouver: Copy

AFRASIABIAN SH., HAJI BAGHERI K., YOUSEFINEZHAD V., ESMAEILNASAB N., SEYFI SH.. RESPONSE TO HEPATITIS B VACCINE IN HIV-INFECTED PATIENTS. ARMAGHAN DANESH[Internet]. 2007;12(2 (46)):11-17. Available from: https://sid.ir/paper/388262/en

IEEE: Copy

SH. AFRASIABIAN, K. HAJI BAGHERI, V. YOUSEFINEZHAD, N. ESMAEILNASAB, and SH. SEYFI, “RESPONSE TO HEPATITIS B VACCINE IN HIV-INFECTED PATIENTS,” ARMAGHAN DANESH, vol. 12, no. 2 (46), pp. 11–17, 2007, [Online]. Available: https://sid.ir/paper/388262/en

Related Journal Papers