Effect of Manufacturing Route on Microstructure and Mechanical Properties of Calcium Phosphate/Gelatin-Starch Composite Scaffold

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Darvishian Haghighi Faezeh; Mollazadeh Beidokhti Sahar; Sahebian Saghi Samaneh; TAYARANI NAJARAN ZAHRA

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Journal: METALLURGICAL ENGINEERING Year:2019 | Volume:22 | Issue:2 (74) Page(s): 84-95

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Title

Effect of Manufacturing Route on Microstructure and Mechanical Properties of Calcium Phosphate/Gelatin-Starch Composite Scaffold

Author(s)

Darvishian Haghighi Faezeh | Mollazadeh Beidokhti Sahar | Sahebian Saghi Samaneh | TAYARANI NAJARAN ZAHRA | Issue Writer Certificate

Keywords

ScaffoldQ2

GelatinQ2

StarchQ1

Calcium Phosphate ParticlesQ1

flexural StrengthQ2

Abstract

There are plenty of bone damages due to different reasons these days. In order to heal of damaged area, utilizing of the Scaffold is necessary. The main aim of this research is fabrication and investigation of Calcium Phosphate/Gelatin-Starch composite Scaffolds. After synthesizing the Calcium Phosphate Particles via sol gel route, three different methods were used to manufacture Calcium Phosphate/ Gelatin Scaffolds. The method which has the porous structure was selected as the main method for fabricating Calcium Phosphate/ Gelatin-Starch Scaffolds. Weight percentage of Starch and applying the Gelatin-Glutaraldehyde coating were chosen as two variations. According to mechanical properties results, the sample with 60 weight percentage of Gelatin and 40 weight percentage of Starch has the highest final flexural Strength which are 4. 5 and 2. 3 MPa for samples with and without Gelatin-Glutaraldehyde coating respectively. The SEM results show the completely porous structure with interconnected pores on the surface of coated samples and some local pores in internal parts of the Scaffolds. According to the result of cell culture, these Scaffolds provide surfaces that facilitate the response of stem cells related to attachment, survival, and proliferation.

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APA: Copy

Darvishian Haghighi, Faezeh, Mollazadeh Beidokhti, Sahar, Sahebian Saghi, Samaneh, & TAYARANI NAJARAN, ZAHRA. (2019). Effect of Manufacturing Route on Microstructure and Mechanical Properties of Calcium Phosphate/Gelatin-Starch Composite Scaffold. METALLURGICAL ENGINEERING, 22(2 (74) ), 84-95. SID. https://sid.ir/paper/389693/en

Vancouver: Copy

Darvishian Haghighi Faezeh, Mollazadeh Beidokhti Sahar, Sahebian Saghi Samaneh, TAYARANI NAJARAN ZAHRA. Effect of Manufacturing Route on Microstructure and Mechanical Properties of Calcium Phosphate/Gelatin-Starch Composite Scaffold. METALLURGICAL ENGINEERING[Internet]. 2019;22(2 (74) ):84-95. Available from: https://sid.ir/paper/389693/en

IEEE: Copy

Faezeh Darvishian Haghighi, Sahar Mollazadeh Beidokhti, Samaneh Sahebian Saghi, and ZAHRA TAYARANI NAJARAN, “Effect of Manufacturing Route on Microstructure and Mechanical Properties of Calcium Phosphate/Gelatin-Starch Composite Scaffold,” METALLURGICAL ENGINEERING, vol. 22, no. 2 (74) , pp. 84–95, 2019, [Online]. Available: https://sid.ir/paper/389693/en

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