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Information Journal Paper

Title

A review of the SARS-Cov-2 immunological study

Pages

  613-620

Abstract

 Introduction: COVID-19 is a highly contagious infectious disease caused by a new coronavirus that can be transmitted from person to person through close contact. The aim of the present study is to investigate new information in the field of COVID-19 immunology. Materials and Methods: The present study uses Google and Google Scholar search engines and articles indexed by reputable international scientific databases including Pub Med, MedLine, and the World Health Organization (WHO). In this study, published articles about COVID-19 and field of immunology were reviewed, and articles that did not have free access (Open Acess) and only access to abstracts were excluded from the study. Results: In total, studies have been suggested that the amount of cytokines such as IL-10, IL-7, IL-2, G-CSF, and TNF-α has been reported at high levels in patients. The ACE2 receptor is the target receptor for the COVID-19 virus, which binds to it after entering the lungs then IFN-I inhibit the primary replication and inhibition of the virus. Conclusion: After reviewing the articles, it was found that strengthening the immune system against viral infections is very important. The virus weakens the immune system by disrupting the production of type I interferon and reducing expression in the production of MHC-I, II. One of the best ways to fight COVID-19 is to get the right vaccine to boost immune system and produce T cells and cytokines.

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    Cite

    APA: Copy

    Emadi, Mahdieh, TAGHINEJAD, JAVID, & Ghaffarzadeh, Ayda. (2021). A review of the SARS-Cov-2 immunological study. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 27(5 ), 613-620. SID. https://sid.ir/paper/392665/en

    Vancouver: Copy

    Emadi Mahdieh, TAGHINEJAD JAVID, Ghaffarzadeh Ayda. A review of the SARS-Cov-2 immunological study. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;27(5 ):613-620. Available from: https://sid.ir/paper/392665/en

    IEEE: Copy

    Mahdieh Emadi, JAVID TAGHINEJAD, and Ayda Ghaffarzadeh, “A review of the SARS-Cov-2 immunological study,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 5 , pp. 613–620, 2021, [Online]. Available: https://sid.ir/paper/392665/en

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