EFFECT OF L-ARGININE SUPPLEMENTATION ON ANTIOXIDANT ENZYME ACTIVITY, TOTAL ANTIOXIDANT CAPACITY AND BODY COMPOSITION IN PATIENTS WITH PRE-DIABETES

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FAZELIAN SIAVASH; SAEDISOMEOLIA AHMAD; MIRFATAHI MARYAM; HOSSEINI MOSTAFA; SADRZADEH YEGANEH HALEH; HESHMATI JAVAD; NAMAZI NAZLI

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Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2013 | Volume:16 | Issue:9 (78) Page(s): 0-0

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Title

EFFECT OF L-ARGININE SUPPLEMENTATION ON ANTIOXIDANT ENZYME ACTIVITY, TOTAL ANTIOXIDANT CAPACITY AND BODY COMPOSITION IN PATIENTS WITH PRE-DIABETES

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Keywords

ANTIOXIDANTSQ2

L-ARGININEQ2

PREDIABETESQ2

Abstract

Background: Considering that pre-diabetes is one of disorders that increases developing of diabetes, this study was performed to investigate the effect of L-ARGININE supplementation on antioxidant enzyme activity, total antioxidant capacity, and body composition in patients with pre-diabetes.Materials and Methods: A double-blinded randomized clinical trial was performed on 46 pre-diabetic patients. Patients in intervention (n=23) and placebo groups received 3g/day Larginine and placebo (three 1gr L-ARGININE capsules), respectively for 8weeks. Anthropometric, body composition, and dietary intake assessments, and also biochemical tests were done at baseline and end of study. Total Antioxidant Capacity (TAC), glutathione peroxidase enzyme and superoxide dismutase activity were measured. Paired t-test, independent t-test and ANOVA were used to analyze quantitative variables.Results: Thirty eight patients (19 subjects in each group) completed the study. After adjusting confounding factors, no significant difference in body composition, anthropometric indices and dietary intake was observed at the end of study (p<0.05 in all factors), but a significant difference in TAC level was observed in the intevention group at the end of study (p<0.001).Conclusion: Supplemenation with 3gr/day L- arginine for 8 weeks led to raised serum TAC level without changes in body composition in pre-diabetic patients.

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APA: Copy

FAZELIAN, SIAVASH, SAEDISOMEOLIA, AHMAD, MIRFATAHI, MARYAM, HOSSEINI, MOSTAFA, SADRZADEH YEGANEH, HALEH, HESHMATI, JAVAD, & NAMAZI, NAZLI. (2013). EFFECT OF L-ARGININE SUPPLEMENTATION ON ANTIOXIDANT ENZYME ACTIVITY, TOTAL ANTIOXIDANT CAPACITY AND BODY COMPOSITION IN PATIENTS WITH PRE-DIABETES. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 16(9 (78)), 0-0. SID. https://sid.ir/paper/392911/en

Vancouver: Copy

FAZELIAN SIAVASH, SAEDISOMEOLIA AHMAD, MIRFATAHI MARYAM, HOSSEINI MOSTAFA, SADRZADEH YEGANEH HALEH, HESHMATI JAVAD, NAMAZI NAZLI. EFFECT OF L-ARGININE SUPPLEMENTATION ON ANTIOXIDANT ENZYME ACTIVITY, TOTAL ANTIOXIDANT CAPACITY AND BODY COMPOSITION IN PATIENTS WITH PRE-DIABETES. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2013;16(9 (78)):0-0. Available from: https://sid.ir/paper/392911/en

IEEE: Copy

SIAVASH FAZELIAN, AHMAD SAEDISOMEOLIA, MARYAM MIRFATAHI, MOSTAFA HOSSEINI, HALEH SADRZADEH YEGANEH, JAVAD HESHMATI, and NAZLI NAMAZI, “EFFECT OF L-ARGININE SUPPLEMENTATION ON ANTIOXIDANT ENZYME ACTIVITY, TOTAL ANTIOXIDANT CAPACITY AND BODY COMPOSITION IN PATIENTS WITH PRE-DIABETES,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 16, no. 9 (78), pp. 0–0, 2013, [Online]. Available: https://sid.ir/paper/392911/en

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