EFFICACY AND SAFETY OF BATH PUVA THERAPY IN THE TREATMENT OF VITILIGO

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FARNAGHI F.; SEYRAFI H.; EHSANI A.H.; MAHMOUD ROBATI R.; EBRAHIMPOUR P.

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2005 | Volume:62 | Issue:12 Page(s): 988-993

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Title

EFFICACY AND SAFETY OF BATH PUVA THERAPY IN THE TREATMENT OF VITILIGO

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Keywords

VITILIGOQ4

BATH PUVAQ4

EFFEICACYQ4

SAFETYQ4

Abstract

Background: VITILIGO is an acquired pigmenting disorder which results from destruction of melanocyte and its prevalence is about one percent among the population. This study was conducted to determine efficacy and SAFETY of BATH PUVA therapy in the treatment of VITILIGO.Patients and Methods: In this step 1-clinical trial, 38 patients with VITILIGO who fulfill the inclusion criteria and lack the exclusion criteria were treated with BATH PUVA. The response defined as repigmentation after treatment and divided to four groups: excellent (more than 75%), good (50-75%), moderate (25-50%) and poor (less than 25%). More over the side-effect were recorded.Results: From 38 patients, 26 cases have poor response, 10 cases show moderate response, 2 cases show good response and no case shows excellent response. The average of response was 23.5%. In this study there is no meaningful relationship between age, gender and duration of disease with rate of remission but it seems number of therapeutic sessions and site of involvement have this relation with the rate of remission (P<0.005). Short-term effect after treatment are as follows: 3 cases of burn (7%), 3 cases of erythema (7%) and one case of bulla. According to the limitation in the length of treatment and follow-up, there is no comment about long-term side effects.Conclusion: Remission after treatment with BATH PUVA only relates to site of involvement and number of therapeutic sessions and there is no relation with age, gender, duration of disease with the rate of remission. This fact is true about the side-effect and no relation was found between age, gender and number of therapeutic session with the rate of side-effects.

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APA: Copy

FARNAGHI, F., SEYRAFI, H., EHSANI, A.H., MAHMOUD ROBATI, R., & EBRAHIMPOUR, P.. (2005). EFFICACY AND SAFETY OF BATH PUVA THERAPY IN THE TREATMENT OF VITILIGO. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 62(12), 988-993. SID. https://sid.ir/paper/39534/en

Vancouver: Copy

FARNAGHI F., SEYRAFI H., EHSANI A.H., MAHMOUD ROBATI R., EBRAHIMPOUR P.. EFFICACY AND SAFETY OF BATH PUVA THERAPY IN THE TREATMENT OF VITILIGO. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2005;62(12):988-993. Available from: https://sid.ir/paper/39534/en

IEEE: Copy

F. FARNAGHI, H. SEYRAFI, A.H. EHSANI, R. MAHMOUD ROBATI, and P. EBRAHIMPOUR, “EFFICACY AND SAFETY OF BATH PUVA THERAPY IN THE TREATMENT OF VITILIGO,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 62, no. 12, pp. 988–993, 2005, [Online]. Available: https://sid.ir/paper/39534/en

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