INDUCTION OF LABOR IN TERM PREGNANCY: SUBLINGUALVERSUS BUCCAL MISOPROSTOL

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HAJ-SEYED JAVADI EZAT SADAT; MOVAHED FARIDEH; Akbari Razieh

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Journal: Tehran University Medical Journal Year:2018 | Volume:76 | Issue:4 Page(s): 250-256

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Title

INDUCTION OF LABOR IN TERM PREGNANCY: SUBLINGUALVERSUS BUCCAL MISOPROSTOL

Author(s)

HAJ-SEYED JAVADI EZAT SADAT | MOVAHED FARIDEH | Akbari Razieh | Issue Writer Certificate

Keywords

BUCCALQ1

MISOPROSTOLQ2

PREGNANCYQ3

SUBLINGUALQ1

Abstract

Background: Labor induction is one of the most public ways carried out global fordelivering mothers. The aim of labor induction is to encourage uterine contractionsbefore the spontaneous onset of labor, resultant in vaginal delivery MISOPROSTOL is usedoff-label for a variety of indications in the practice of obstetrics and gynecology, including medication abortion, medical management of miscarriage, induction of labor, cervical ripening before surgical procedures, and the treatment of postpartumhemorrhage. Regarding the importance and lack of similar researches in Iran, thisresearch was done to compare the efficacy of BUCCAL and SUBLINGUAL MISOPROSTOL forlabor induction in pregnant women. Methods: This study was conducted as a randomized double-blind clinical trial fromMarch 2017 to February 2018. In this survey, 200 women were randomly assigned toreceive 50 μ g BUCCAL MISOPROSTOL and SUBLINGUAL (100 BUCCAL and 100 SUBLINGUAL) inKosar Hospital, Qazvin University of Medical Sciences, Iran. The maternal and fetalcomplications, Bishop score, and time of pain onset and its interval with labor weremonitored in two groups and the findings were analyzed. Results: Research variables were age, gestational age, BMI, number of previouspregnancy, neonatal weight, total dose, Bishop score 1, Bishop score 6, oxytocin, anddelivery type. The results showed that there were no differences between Bishop score6 (P=0. 07), and 1 (P=0. 36), total dose (P=0. 58), neonatal weight (P=0. 43), number ofpregnancy (P=0. 67), BMI (P=0. 67), and PREGNANCY weak (P=0. 108) of SUBLINGUAL groupand BUCCAL group. About 43 patients (43%) in BUCCAL and 64 (64%) in SUBLINGUAL grouphad vaginal delivery (P=0. 05). The frequencies of maternal and fetal complicationswere similar between two groups. Conclusion: It can be concluded that there is no difference between efficacy ofsublingual and BUCCAL MISOPROSTOL in PREGNANCY results, maternal, and fetalcomplications, however, it seems that the SUBLINGUAL group is more effective thanBUCCAL group due to the significant amount of vaginal delivery, achieving vaginaldelivery in less than 24 hours, and less need for oxytocin.

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APA: Copy

HAJ-SEYED JAVADI, EZAT SADAT, MOVAHED, FARIDEH, & Akbari, Razieh. (2018). INDUCTION OF LABOR IN TERM PREGNANCY: SUBLINGUALVERSUS BUCCAL MISOPROSTOL. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 76(4 ), 250-256. SID. https://sid.ir/paper/39620/en

Vancouver: Copy

HAJ-SEYED JAVADI EZAT SADAT, MOVAHED FARIDEH, Akbari Razieh. INDUCTION OF LABOR IN TERM PREGNANCY: SUBLINGUALVERSUS BUCCAL MISOPROSTOL. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2018;76(4 ):250-256. Available from: https://sid.ir/paper/39620/en

IEEE: Copy

EZAT SADAT HAJ-SEYED JAVADI, FARIDEH MOVAHED, and Razieh Akbari, “INDUCTION OF LABOR IN TERM PREGNANCY: SUBLINGUALVERSUS BUCCAL MISOPROSTOL,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 76, no. 4 , pp. 250–256, 2018, [Online]. Available: https://sid.ir/paper/39620/en

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