DIAGNOSTIC VALUE OF PLEURAL ADENOSINE DEAMINASE ACTIVITY IN DISCRIMINATION OF EXUDATIVE FROM TRANSUDATIVE EFFUSION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAZI E.; MOLAGHANBARI M.R.; AKBARI HOSSEIN; EHTERAM H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Feyz Medical Sciences Journal Year:2009 | Volume:13 | Issue:3 (SERIAL 51) Page(s): 195-201

Download Full-Text

Persian Verion

View:

811

Download:

Cites:

Information Journal Paper

Title

DIAGNOSTIC VALUE OF PLEURAL ADENOSINE DEAMINASE ACTIVITY IN DISCRIMINATION OF EXUDATIVE FROM TRANSUDATIVE EFFUSION

Author(s)

RAZI E. | MOLAGHANBARI M.R. | AKBARI HOSSEIN | EHTERAM H. | Issue Writer Certificate

Keywords

ADENOSINE DEAMINASEQ3

PLEURAL EFFUSIONQ3

TRANSUDATES AND EXUDATESQ3

Abstract

Background: The differentiation of PLEURAL EFFUSIONs as exudates or transudates is the first step in the diagnosis of PLEURAL EFFUSIONs. The aim of this study was to evaluate the usefulness of pleural ADENOSINE DEAMINASE (PADA), for separating transudative PLEURAL EFFUSION from exudative PLEURAL EFFUSION.Materials and Methods: Using light's criteria, after careful evaluation of all relevant clinical and biochemical parameters of pleural fluid and serum, classically effusions were classified to transudative or exudative. The means and standard deviations of PADA, and pleural/serum ADA (P/S ADA) ratio were calculated for transudative and exudative effusions .The best cut-off values for each test were identified by using the receiver operating characteristic (ROC) curve.Results: We compared PADA levels between transudative and exudative patients with PLEURAL EFFUSION. According to the criteria used, 32 patients were included in the transudate group and 73 patients in the exudate group. Pleural fluid ADA levels were significantly lower in the transudate group than in exudate one (16.21±6.10 U/lit vs. 22.24±7.50 U/lit; P<0.001). Also the mean pleural fluid/serum ADA ratio were (P<0.0001) lower in transudates as compared to exudates (0.76±0.32 vs. 0.91±0.26; P=0.021). Using a cut-off point of 14.5 IU/L, the sensitivity and specificity of pleural ADA in the diagnosis of exudates was computed to be 84.7% and 48.3% respectively. At a cut-off point 0.75, pleural fluid/serum ADA ratio was found to have sensitivity and specificity of 73.2% and 65.5%, respectively.Conclusion: Measuring PADA is suggested as a useful biochemical marker in differentiating between pleural exudates and transudates.

Cites

No record.

References

No record.

Cite

APA: Copy

RAZI, E., MOLAGHANBARI, M.R., AKBARI, HOSSEIN, & EHTERAM, H.. (2009). DIAGNOSTIC VALUE OF PLEURAL ADENOSINE DEAMINASE ACTIVITY IN DISCRIMINATION OF EXUDATIVE FROM TRANSUDATIVE EFFUSION. FEYZ, 13(3 (SERIAL 51)), 195-201. SID. https://sid.ir/paper/398681/en

Vancouver: Copy

RAZI E., MOLAGHANBARI M.R., AKBARI HOSSEIN, EHTERAM H.. DIAGNOSTIC VALUE OF PLEURAL ADENOSINE DEAMINASE ACTIVITY IN DISCRIMINATION OF EXUDATIVE FROM TRANSUDATIVE EFFUSION. FEYZ[Internet]. 2009;13(3 (SERIAL 51)):195-201. Available from: https://sid.ir/paper/398681/en

IEEE: Copy

E. RAZI, M.R. MOLAGHANBARI, HOSSEIN AKBARI, and H. EHTERAM, “DIAGNOSTIC VALUE OF PLEURAL ADENOSINE DEAMINASE ACTIVITY IN DISCRIMINATION OF EXUDATIVE FROM TRANSUDATIVE EFFUSION,” FEYZ, vol. 13, no. 3 (SERIAL 51), pp. 195–201, 2009, [Online]. Available: https://sid.ir/paper/398681/en

Related Journal Papers