Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

542
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Effects of the stimulation of β 2-adrenoceptors of the the basolateral amygdala on anxiety-like behaviors following electrical foot-shock stress in male rat

Pages

  250-259

Abstract

 Introduction: The basolateral Amygdala (BLA) is a key structure that integrated Anxiety information. It is suggested that baso-lateral area of Amygdala receives a dense norepinephrine innervation from the locus coeruleus nucleus. Furthermore, Stress increased norepinephrine secretion in the BLA. In the present study, we examined the effects of the stimulation of β 2-adrenoceptors in the BLA on Anxiety-like behaviors following foot-shock Stress. Materials and Methods: Foot-shock Stress (10 Hz, 40 mV for 60 seconds) for 4 consecutive days applied to animals. Salbutamol (the β 2-adrenoreceptor agonist; 4 µ g/rat) bilaterally injected into the BLA 5 min before starting foot-shock Stress for 4 consecutive days. Anxiety-like behaviors assessed 24h after the last session of Stress, using elevated plus-maze (EPM) and Open Field Test (OFT). Results: Foot-shock Stress significantly decreased time spent and the number of entries into the open arms of EPM. Similarly, Stress significantly decreased the time spent and the number of entries into the center area of OFT. Furthermore, foot-shock Stress significantly decreased the number of grooming and rearing behaviors. Additionally, intra-BLA infusions of salbutamol before Stress significantly increased time spent and the number of entries into the open arms as compared with Stress group. In addition, OFT results showed that salbutamol increased the time spent in the center, number of center entries, the number of rearing and grooming behaviors, line crossing and total distance as compared with the Stress group. Conclusion: It is likely that β 2-adrenoceptors of the BLA mediate the induced-Anxiety-behaviors by foot-shock Stress.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    MEFTAHI, GHOLAM HOSSEIN, Pirzad Jahromi, Gila, Gholipour, Nazila, & BAHARI, ZAHRA. (2021). Effects of the stimulation of β 2-adrenoceptors of the the basolateral amygdala on anxiety-like behaviors following electrical foot-shock stress in male rat. KOOMESH, 23(2 (82) ), 250-259. SID. https://sid.ir/paper/400849/en

    Vancouver: Copy

    MEFTAHI GHOLAM HOSSEIN, Pirzad Jahromi Gila, Gholipour Nazila, BAHARI ZAHRA. Effects of the stimulation of β 2-adrenoceptors of the the basolateral amygdala on anxiety-like behaviors following electrical foot-shock stress in male rat. KOOMESH[Internet]. 2021;23(2 (82) ):250-259. Available from: https://sid.ir/paper/400849/en

    IEEE: Copy

    GHOLAM HOSSEIN MEFTAHI, Gila Pirzad Jahromi, Nazila Gholipour, and ZAHRA BAHARI, “Effects of the stimulation of β 2-adrenoceptors of the the basolateral amygdala on anxiety-like behaviors following electrical foot-shock stress in male rat,” KOOMESH, vol. 23, no. 2 (82) , pp. 250–259, 2021, [Online]. Available: https://sid.ir/paper/400849/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top