TRAMADOL WITHDRAWAL IN A NEONATE: A CASE REPORT

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BORNA HAJIE; BORNA SEDIGHE

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Journal: Tehran University Medical Journal Year:2012 | Volume:70 | Issue:6 Page(s): 0-0

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Title

TRAMADOL WITHDRAWAL IN A NEONATE: A CASE REPORT

Author(s)

BORNA HAJIE | BORNA SEDIGHE | Issue Writer Certificate

Keywords

NEONATEQ2

TRAMADOLQ2

WITHDRAWAL SYNDROMEQ3

Abstract

Background: TRAMADOL is a synthetics 4-phenyl-piperidine analogue of codeine used for treating moderate to severe pain. TRAMADOL is a FDA pregnancy category C medication which induces release of serotonin and inhibits the reuptake of norepinephrine. Chronic use of this drug during pregnancy may lead to physical dependency and WITHDRAWAL SYNDROME in the NEONATE.Case presentation: We report the newborn of a woman admitted in the delivery ward of Mostafa Khomeini Hospital in Tehran, Iran in 2011. The mother suffered from chronic low back pain and headache and frequently took TRAMADOL during pregnancy. The infant had a gestational age of 38.5 w, a birth weight of 2950 gr and an Apgar score of 9/10 at 1 and 5 minutes after birth.The first signs of WITHDRAWAL SYNDROME occurred after 24 h with nausea, vomiting, poor feeding, and tremor. Later, agitation, tremor, hyprertonicity, and repeated multifocal myoclonus, and generalized tonic-clonic seizures developed. Clinical signs of WITHDRAWAL SYNDROME waned under phenobarbital therapy.Conclusion: Drug WITHDRAWAL SYNDROME should be considered in the NEONATEs of pregnant mothers who chronically take TRAMADOL. TRAMADOL administration during pregnancy should be restricted to carefully selected cases.

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APA: Copy

BORNA, HAJIE, & BORNA, SEDIGHE. (2012). TRAMADOL WITHDRAWAL IN A NEONATE: A CASE REPORT. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 70(6), 0-0. SID. https://sid.ir/paper/400968/en

Vancouver: Copy

BORNA HAJIE, BORNA SEDIGHE. TRAMADOL WITHDRAWAL IN A NEONATE: A CASE REPORT. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2012;70(6):0-0. Available from: https://sid.ir/paper/400968/en

IEEE: Copy

HAJIE BORNA, and SEDIGHE BORNA, “TRAMADOL WITHDRAWAL IN A NEONATE: A CASE REPORT,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 70, no. 6, pp. 0–0, 2012, [Online]. Available: https://sid.ir/paper/400968/en

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