Elemental analysis of tissue in proton therapy using photopeak count of prompt gamma spectrum

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Saheli f.; VOSOUGHI N.; RIAZI Z.; RASOULI F.S.

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Journal: JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY Year:2020 | Volume:41 | Issue:2 (92) Page(s): 1-9

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Title

Elemental analysis of tissue in proton therapy using photopeak count of prompt gamma spectrum

Author(s)

Saheli f. | VOSOUGHI N. | RIAZI Z. | RASOULI F.S. | Issue Writer Certificate

Keywords

Monte carloQ2

Proton therapyQ1

Geant4Q1

Prompt gammaQ1

Elemental analysisQ2

Abstract

Online Elemental analysis of irradiated tissue in Proton therapy is a major part of this treatment, since it leads to accurate estimation of the depth of Bragg peak, proton range, and distribution of stopping power of irradiated tissue. Given the fact that each element has unique characteristic Prompt gamma (PG) spectrum, recording and analyzing of the emitted gamma-ray spectra is one of the methods used for online Elemental analysis of irradiated tissue. In the present study, the PG lines of most abundant elements of human tissues (12C, 16O, 20Ca, and 14N) are obtained using Geant4 toolkit. Moreover, the linear dependency of 7. 12, 3. 91 and 2. 31 MeV PG counts to the mass of 16O, 20Ca, and 14N are investigated in five phantoms. The gamma lines of 2. 31, 3. 91 and 7. 12 MeV are selected to determine the mass of nitrogen, calcium, and oxygen in the irradiated volume. Furthermore, for two test phantoms, the mass of elements is estimated using linear fitting and is compared with predefined mass of these elements in the test phantoms. The results showed that the relative errors of estimated mass of calcium, nitrogen, and oxygen are less than 6%, which leads to the range estimation deviation of about 1 mm.

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APA: Copy

Saheli, f., VOSOUGHI, N., RIAZI, Z., & RASOULI, F.S.. (2020). Elemental analysis of tissue in proton therapy using photopeak count of prompt gamma spectrum. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, 41(2 (92) ), 1-9. SID. https://sid.ir/paper/404311/en

Vancouver: Copy

Saheli f., VOSOUGHI N., RIAZI Z., RASOULI F.S.. Elemental analysis of tissue in proton therapy using photopeak count of prompt gamma spectrum. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY[Internet]. 2020;41(2 (92) ):1-9. Available from: https://sid.ir/paper/404311/en

IEEE: Copy

f. Saheli, N. VOSOUGHI, Z. RIAZI, and F.S. RASOULI, “Elemental analysis of tissue in proton therapy using photopeak count of prompt gamma spectrum,” JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, vol. 41, no. 2 (92) , pp. 1–9, 2020, [Online]. Available: https://sid.ir/paper/404311/en

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