مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

652
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Application of mesoporous silica nanoparticles for drug delivery to cancer cells

Pages

  220-230

Keywords

Mesoporous Silica Nanoparticles (MSNs)Q2

Abstract

 Cancer is one of the main causes of death worldwide. Chemotherapy is the most common method for Cancer therapy which represent non-specific side effects on normal cells and tissues and drug resistance in Cancer cells. There are two main mechanisms for Multi Drug Resistance (MDR) in Cancer cells including: drug efflux pump and activation of anti-apoptotic pathways. Cancer chemotherapy disadvantages can be overcome by using nanoparticulate drug delivery systems like Mesoporous Silica Nanoparticles (MSNs) that have been used as drug delivery system since 2001. The present review included synthesis, targeted (active or passive) drug delivery to Cancer cells, co-delivery of antiCancer drugs and siRNA by MSNs and its toxicity. This review revealed that MSNs are good candidate for drug delivery to Cancer cells due to its unique properties including: controllable pore and particle sizes, thermal and chemical stability, modifications of outer and inner surfaces of nanoparticles for drug and siRNA loading, attachment of ligand for Targeted Drug Delivery, high drug loading capacity and controlled drug release, biocompatibility and biodegradation in aqueous medium.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    MALAEKEH NIKOUEI, BIZHAN, & Hanafi Bojd, Mohammad Yahya. (2020). Application of mesoporous silica nanoparticles for drug delivery to cancer cells. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 27(3 ), 220-230. SID. https://sid.ir/paper/405661/en

    Vancouver: Copy

    MALAEKEH NIKOUEI BIZHAN, Hanafi Bojd Mohammad Yahya. Application of mesoporous silica nanoparticles for drug delivery to cancer cells. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(3 ):220-230. Available from: https://sid.ir/paper/405661/en

    IEEE: Copy

    BIZHAN MALAEKEH NIKOUEI, and Mohammad Yahya Hanafi Bojd, “Application of mesoporous silica nanoparticles for drug delivery to cancer cells,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 3 , pp. 220–230, 2020, [Online]. Available: https://sid.ir/paper/405661/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top