COMPARISON OF CLINICAL RESPONSE TO ZATARIA MULTIFLORA VAGINAL CREAM AND BORIC ACID IN PATIENTS WITH RECURRENT VULVOVAGINAL CANDIDIASIS

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RABIEE MARYAM; AKBARI HOSSEIN; NASERI MOHSEN; BEKHRADI REZA; NIKZAD MARYAM; TORKESTANI FARAHNAZ

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Journal: DANESHVAR MEDICINE Year:2012 | Volume:20 | Issue:102 Page(s): 0-0

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Title

COMPARISON OF CLINICAL RESPONSE TO ZATARIA MULTIFLORA VAGINAL CREAM AND BORIC ACID IN PATIENTS WITH RECURRENT VULVOVAGINAL CANDIDIASIS

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Keywords

CANDIDIASISQ3

RECURRENT VULVOVAGINAL CANDIDIASISQ2

BORIC ACIDQ3

ZATARIA MULTIFLORAQ2

Abstract

Background and Objective: Since long-term therapy of recurrent vulvovaginal CANDIDIASIS patients with azol is accompanied with drug resistance and systemic toxicity, thus, researches have returned to nonazole drugs. This research compared clinical response of these patients to BORIC ACID and leukorex (Zataria multiflora).Materials and Methods: This study was performed as a blind clinical trial in control with positive cases (parallel). Patients with recurrent vulvovaginal CANDIDIASIS that had a positive culture without any predisposing factors were enrolled in this survey. Vaginal cream of ZATARIA MULTIFLORA 1% and BORIC ACID 3% were given blindly. Signs and symptoms on first visit, and 1 and 6 months after starting treatment was analyzed using chi square, Mann-Whitney and t tests.Results: In BORIC ACID group, the score of severity signs initially was 9±3.3 that got to 3.48±3.8 and 3.33±5.1 in first and second periods of therapy, respectively. In ZATARIA MULTIFLORA group, the score of severity signs initially was 8.21±3.6 that got to 2.52±2.46 and 3.36±3.7 in first and second periods of therapy, respectively. The reduced scores of two groups were significant (p</001). The final cure rate was 74.2% and 64.5% in BORIC ACID and ZATARIA MULTIFLORA groups, respectively that there was not a significant difference between the two groups.Conclusion: ZATARIA MULTIFLORA is considers as an alternative drug in treatment of patients with recurrent vulvovaginal CANDIDIASIS.

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APA: Copy

RABIEE, MARYAM, AKBARI, HOSSEIN, NASERI, MOHSEN, BEKHRADI, REZA, NIKZAD, MARYAM, & TORKESTANI, FARAHNAZ. (2012). COMPARISON OF CLINICAL RESPONSE TO ZATARIA MULTIFLORA VAGINAL CREAM AND BORIC ACID IN PATIENTS WITH RECURRENT VULVOVAGINAL CANDIDIASIS. DANESHVAR MEDICINE, 20(102), 0-0. SID. https://sid.ir/paper/405937/en

Vancouver: Copy

RABIEE MARYAM, AKBARI HOSSEIN, NASERI MOHSEN, BEKHRADI REZA, NIKZAD MARYAM, TORKESTANI FARAHNAZ. COMPARISON OF CLINICAL RESPONSE TO ZATARIA MULTIFLORA VAGINAL CREAM AND BORIC ACID IN PATIENTS WITH RECURRENT VULVOVAGINAL CANDIDIASIS. DANESHVAR MEDICINE[Internet]. 2012;20(102):0-0. Available from: https://sid.ir/paper/405937/en

IEEE: Copy

MARYAM RABIEE, HOSSEIN AKBARI, MOHSEN NASERI, REZA BEKHRADI, MARYAM NIKZAD, and FARAHNAZ TORKESTANI, “COMPARISON OF CLINICAL RESPONSE TO ZATARIA MULTIFLORA VAGINAL CREAM AND BORIC ACID IN PATIENTS WITH RECURRENT VULVOVAGINAL CANDIDIASIS,” DANESHVAR MEDICINE, vol. 20, no. 102, pp. 0–0, 2012, [Online]. Available: https://sid.ir/paper/405937/en

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