The Effect of Six Week Resistance Training on Muscle Regeneration in Tumor-Bearing BALB-C Mice

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Asadmanesh E.; Koushkie Jahromi Maryam; DARYANOOSH F.; Neamati j.; MOJTAHEDI Z.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2019 | Volume:9 | Issue:3 Page(s): 1507-1514

Download Full-Text

Persian Verion

View:

449

Download:

3,247

Cites:

Information Journal Paper

Title

The Effect of Six Week Resistance Training on Muscle Regeneration in Tumor-Bearing BALB-C Mice

Author(s)

Keywords

CachexiaQ1

muscular regenerationQ1

resistance trainingQ1

PAX7Q1

eMHCQ1

Abstract

Background & Objective: Many cancer patients suffer from Cachexia or cancer-induced muscle atrophy. Cachexia can have various causes one of which is the reduction of muscle regeneration. resistance training has been suggested as one of the proper stimulator of increasing muscular regeneration. The present study aimed at evaluating the effect of resistance training on two factors of regeneration including PAX7 and eMHC, tumor-free weight and tumor weight of mice. Materials & Methods: This study was a kind of experimental intervention. Subjects of the study included 10 BALB-C mice (age: 6 weeks) which CT-26 tumor was transplanted to them. Mice were divided into two groups of resistance training (n=5) and control (n=5) randomly. Training group performed six-week progressive resistance training and control groups were kept in cages without any exercise intervention. At the end of the experiment, gastrocnemius muscle was taken for evaluating related factors. Data were analyzed using the independent t-test. Results: There was no significant difference in PAX7 between two groups of training and control, but eMHC reduced significantly in training compared to the control group (P=0. 038). Tumor-free bodyweight of training group increased significantly compared to the control group (P=0. 0004) and there was no significant difference in tumor weight between two groups of training and control. Conclusion: Although resistance training does not increase tumor growth but probably reduce some muscle regeneration factors in cancer-bearing mice. So, for improving muscular regeneration in Cachexia bearing patients, probably resistance training is not a good choice. However, more future researches are required.

Cites

No record.

References

Cite

APA: Copy

Asadmanesh, E., Koushkie Jahromi, Maryam, DARYANOOSH, F., Neamati, j., & MOJTAHEDI, Z.. (2019). The Effect of Six Week Resistance Training on Muscle Regeneration in Tumor-Bearing BALB-C Mice. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 9(3 ), 1507-1514. SID. https://sid.ir/paper/406136/en

Vancouver: Copy

Asadmanesh E., Koushkie Jahromi Maryam, DARYANOOSH F., Neamati j., MOJTAHEDI Z.. The Effect of Six Week Resistance Training on Muscle Regeneration in Tumor-Bearing BALB-C Mice. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2019;9(3 ):1507-1514. Available from: https://sid.ir/paper/406136/en

IEEE: Copy

E. Asadmanesh, Maryam Koushkie Jahromi, F. DARYANOOSH, j. Neamati, and Z. MOJTAHEDI, “The Effect of Six Week Resistance Training on Muscle Regeneration in Tumor-Bearing BALB-C Mice,” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 9, no. 3 , pp. 1507–1514, 2019, [Online]. Available: https://sid.ir/paper/406136/en

Related Journal Papers