Effect of Vigorous Aerobic Training on Serum Levels of Some Inhibitory and Excitatory Factors of Angiogenesis in Women with Type 2 Diabetes

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VIZVARI E.; FARZANEGI P.; Abbas Zade Sourati H.

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Journal: Pathobiology Research Year:2018 | Volume:21 | Issue:3 Page(s): 125-131

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Information Journal Paper

Title

Effect of Vigorous Aerobic Training on Serum Levels of Some Inhibitory and Excitatory Factors of Angiogenesis in Women with Type 2 Diabetes

Author(s)

VIZVARI E. | FARZANEGI P. | Abbas Zade Sourati H. | Issue Writer Certificate

Keywords

Type 2 DiabetesQ1

Nitric OxideQ3

Vascular Endothelial Growth FactorQ1

EndostatinQ1

Abstract

Aims Vascular disorder is one of the consequences of diabetes. Physical activity also plays an important role in the improvement of this disorder. Therefore, the aim of this study was to investigate the effect of vigorous aerobic training on serum levels of inhibitory and excitatory factors of Angiogenesis in women with Type 2 Diabetes. Materials & Methods In this quasi-experimental study with pre-test and post-test design that was performed among women with diabetes population in Gorgan in volunteer sampling, 28 women with Type 2 Diabetes in Gorgan were selected By … sampling method and were divided into training and control groups (14 individuals each group). Training intervention consisted 8 weeks of vigorous aerobic exercise (70%-80%) with 3 times per week. Just before the exercise and 48 hours after that, serum levels of Nitric Oxide (NO), Vascular Endothelial Growth Factor (VEGF), and Endostatin (ES) were evaluated. The data were analyzed by SPSS24 software, using repeated measures ANOVA. Findings Eight weeks of aerobic training caused a significant increase in serum levels of NO (p=0. 016), VEGF (p=0. 036), and an insignificant increase in ES (p=0. 237). Also, a significant decrease was observed in fasting blood glucose (p=0. 027) and A1C (p=0. 003) compared to the control group. Conclusion Regular aerobic exercise improves serum levels of angiogenesis-related and metabolic factors in women with Type 2 Diabetes.

Cites

Effect of Moderate Aerobic Exercise on Serum Levels of FGF21 and Fetuin A in Women with Type 2 Diabetes

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APA: Copy

VIZVARI, E., FARZANEGI, P., & Abbas Zade Sourati, H.. (2018). Effect of Vigorous Aerobic Training on Serum Levels of Some Inhibitory and Excitatory Factors of Angiogenesis in Women with Type 2 Diabetes. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), 21(3 ), 125-131. SID. https://sid.ir/paper/407408/en

Vancouver: Copy

VIZVARI E., FARZANEGI P., Abbas Zade Sourati H.. Effect of Vigorous Aerobic Training on Serum Levels of Some Inhibitory and Excitatory Factors of Angiogenesis in Women with Type 2 Diabetes. PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES)[Internet]. 2018;21(3 ):125-131. Available from: https://sid.ir/paper/407408/en

IEEE: Copy

E. VIZVARI, P. FARZANEGI, and H. Abbas Zade Sourati, “Effect of Vigorous Aerobic Training on Serum Levels of Some Inhibitory and Excitatory Factors of Angiogenesis in Women with Type 2 Diabetes,” PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), vol. 21, no. 3 , pp. 125–131, 2018, [Online]. Available: https://sid.ir/paper/407408/en

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