EFFECT OF ZINC SUPPLEMENT ON THE COMPLICATIONS OF GESTATIONAL DIABETES

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BEHRASHI M.; FOROUZANFARD F.; ALI ASGHARZADEH A.; MOUSAVI SEYED GHOLAM ABAS

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Journal: Feyz Medical Sciences Journal Year:2009 | Volume:12 | Issue:4 (SERIAL 48) Page(s): 29-33

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Title

EFFECT OF ZINC SUPPLEMENT ON THE COMPLICATIONS OF GESTATIONAL DIABETES

Author(s)

BEHRASHI M. | FOROUZANFARD F. | ALI ASGHARZADEH A. | MOUSAVI SEYED GHOLAM ABAS | Issue Writer Certificate

Keywords

GESTATIONAL DIABETESQ3

ZINC SUPPLEMENTQ2

MACROSOMIAQ3

Abstract

Background: Diabetes, especially the GESTATIONAL DIABETES with its special fetal and maternal disorders, is the most common complication of pregnancy. Both gestational and type II diabetes mellitus are along with a disturbances to insulin secretion as well as insulin resistance. Considering the significant role of zinc in insulin function, the deficiency and importance of this element in GESTATIONAL DIABETES is a matter of consideration. Materials and Methods: This clinical trial was carried out on 60 pregnants suffering from GESTATIONAL DIABETES, and needing insulin injection from 32nd week to full-term. The patients were divided into two groups; the case group (n=30), received daily zinc sulfate (25mg or 5cc) plus insulin and control group (n=30) received daily placebo (5 cc as syrup) plus insulin until the time of delivery. The required insulin dose was regulated through monitoring fasting blood sugar and blood sugar, 2 h postprandial, every two weeks in both groups. These groups were compared in terms of required insulin dose and maternal/fetal complications. Data were analyzed using t-test, OR, CI, Fisher Exact test, Kolmogorov-Smirnov and Chi-Square tests. Results: The required dose of insulin had a significant decrease in the case group compared to the control one (p<0.001). However, the mean change in insulin dose in the case and control group compared to the beginning of study was 8.766 (SD: 9.63) and 17.533 (SD: 10.54), respectively. The incidence of MACROSOMIA in the case and control groups was significant (P<0.01). The odds ratio of control group compared to the case group was 7. The preeclampsia prevalence in both groups was not significant. Conclusion: ZINC SUPPLEMENTation in GESTATIONAL DIABETES may lead to the reduction of required insulin dose, incidence of MACROSOMIA and the related complications (e.g., caesarian and delivery dystocia).

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APA: Copy

BEHRASHI, M., FOROUZANFARD, F., ALI ASGHARZADEH, A., & MOUSAVI, SEYED GHOLAM ABAS. (2009). EFFECT OF ZINC SUPPLEMENT ON THE COMPLICATIONS OF GESTATIONAL DIABETES. FEYZ, 12(4 (SERIAL 48)), 29-33. SID. https://sid.ir/paper/40984/en

Vancouver: Copy

BEHRASHI M., FOROUZANFARD F., ALI ASGHARZADEH A., MOUSAVI SEYED GHOLAM ABAS. EFFECT OF ZINC SUPPLEMENT ON THE COMPLICATIONS OF GESTATIONAL DIABETES. FEYZ[Internet]. 2009;12(4 (SERIAL 48)):29-33. Available from: https://sid.ir/paper/40984/en

IEEE: Copy

M. BEHRASHI, F. FOROUZANFARD, A. ALI ASGHARZADEH, and SEYED GHOLAM ABAS MOUSAVI, “EFFECT OF ZINC SUPPLEMENT ON THE COMPLICATIONS OF GESTATIONAL DIABETES,” FEYZ, vol. 12, no. 4 (SERIAL 48), pp. 29–33, 2009, [Online]. Available: https://sid.ir/paper/40984/en

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