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Information Journal Paper

Title

The Interactive Effect of 6 Weeks of Endurance Training and Stanozolol Steroid Treatment on Hepatic Enzymes in Healthy Male Rats

Pages

  375-389

Abstract

 The aim of this study was to investigate the interactive effect of six weeks of endurance training and treatment of stanozolol steroid on changes of serum levels of ALT, AST and ALP enzymes in male heALThy rats. 32 male Wistar rats (age: 12 weeks, mean initial body weight: 289± 16 g) were divided into four groups: placebo (P, n=8), exercise+placebo (E, n=8), exercise+stanozolol (ES, n=8) and stanozolol (S, n=8). ES and S groups received weekly intramuscular stanozolol injection (5mg/kg of body weight) while P and E groups received the same dosage of arachis oil as placebo. E and ES groups were submitted to a progressive endurance running program on a treadmill with the intensity of 70-75% VO2max for 6 weeks and 5 days per week. ALT, AST and ALP serum levels were measured by ELISA method. KS test was used to determine the normal distribution of data and Leven test was applied to determine the distribution of similar dispersion of groups. Data were analyzed by one-way ANOVA test at (P<0. 05) and Tukey post hoc test was used to determine within-group differences. ALT (P=0. 002) and AST (P=0. 001) changes were significant but ALP serum levels (P=0. 070) were not significant. According to the findings of this study, it can be stated that endurance training did not have a modulating effect on changes of liver enzymes due to stanozolol steroid consumption.

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    APA: Copy

    Joneidi Shariatzade, Alireza, GAEINI, ABBAS ALI, Choobine, Siroos, & MIRZAEI, MARYAM. (2021). The Interactive Effect of 6 Weeks of Endurance Training and Stanozolol Steroid Treatment on Hepatic Enzymes in Healthy Male Rats. SPORT BIOSCIENCES (HARAKAT), 12(4 ), 375-389. SID. https://sid.ir/paper/410057/en

    Vancouver: Copy

    Joneidi Shariatzade Alireza, GAEINI ABBAS ALI, Choobine Siroos, MIRZAEI MARYAM. The Interactive Effect of 6 Weeks of Endurance Training and Stanozolol Steroid Treatment on Hepatic Enzymes in Healthy Male Rats. SPORT BIOSCIENCES (HARAKAT)[Internet]. 2021;12(4 ):375-389. Available from: https://sid.ir/paper/410057/en

    IEEE: Copy

    Alireza Joneidi Shariatzade, ABBAS ALI GAEINI, Siroos Choobine, and MARYAM MIRZAEI, “The Interactive Effect of 6 Weeks of Endurance Training and Stanozolol Steroid Treatment on Hepatic Enzymes in Healthy Male Rats,” SPORT BIOSCIENCES (HARAKAT), vol. 12, no. 4 , pp. 375–389, 2021, [Online]. Available: https://sid.ir/paper/410057/en

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