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Information Journal Paper

Title

Synthesis and Characterization of a Novel Drug Delivery System Based on Immunoglobulin G Nanoparticles and Study of Oxaliplatin Release

Pages

  11-19

Abstract

 Synthesis of stable drug carriers for Drug Delivery based on Immunoglobulin G (IgG) in the release of Oxaliplatin as an anticancer drug was carried out and characterized infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM). In this paper, the drug release tests were performed for pure IgG and two different ratios of drug / IgG nanoparticles (IgG-NPs) (1: 1 and 2: 1). Drug loading and encapsulation were determined for three systems. The results showed that the drug release was sustained in IgG NPs systems in comparison with pure IgG. Also, the release mechanism was studied and indicated that the mechanism was fickian diffusion. Therefore, the designed system is a suitable candidate for drug release of anticancer drugs.

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    APA: Copy

    Shahlaei, Mona, SAEIDIFAR, MARYAM, & ZAMANIAN, ALI. (2020). Synthesis and Characterization of a Novel Drug Delivery System Based on Immunoglobulin G Nanoparticles and Study of Oxaliplatin Release. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), 39(2 (96) ), 11-19. SID. https://sid.ir/paper/411056/en

    Vancouver: Copy

    Shahlaei Mona, SAEIDIFAR MARYAM, ZAMANIAN ALI. Synthesis and Characterization of a Novel Drug Delivery System Based on Immunoglobulin G Nanoparticles and Study of Oxaliplatin Release. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN)[Internet]. 2020;39(2 (96) ):11-19. Available from: https://sid.ir/paper/411056/en

    IEEE: Copy

    Mona Shahlaei, MARYAM SAEIDIFAR, and ALI ZAMANIAN, “Synthesis and Characterization of a Novel Drug Delivery System Based on Immunoglobulin G Nanoparticles and Study of Oxaliplatin Release,” NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), vol. 39, no. 2 (96) , pp. 11–19, 2020, [Online]. Available: https://sid.ir/paper/411056/en

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