THYROID HORMONE LEVELS BEFORE AND AFTER RENAL TRANSPLANTATION IN DIALYSED
AND NORMAL PATIENTS AND THEIR RELATIONSHIP WITH RENAL GRAFT FUNCTION

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HOSSEINI E.A.S.; GHASEMZADEH M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Medical Council of Iran Year:2001 | Volume:19 | Issue:1 Page(s): 16-20

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Title

THYROID HORMONE LEVELS BEFORE AND AFTER RENAL TRANSPLANTATION IN DIALYSED AND NORMAL PATIENTS AND THEIR RELATIONSHIP WITH RENAL GRAFT FUNCTION

Author(s)

HOSSEINI E.A.S. | GHASEMZADEH M. | Issue Writer Certificate

Keywords

RENAL TRANSPLANTATIONQ3

THYROID HORMONESQ4

THYROTROPINQ2

HEMODIALYSISQ3

Abstract

Chronic renal failure is one of the causes of euthyroidism which is associated with some abnormalities in thyroid hormone metabolism. Although dialysis does not significantly affect these abnormalities, but RENAL TRANSPLANTATION leads to improve the conditions. In this study, first serum levels of THYROTROPIN and THYROID HORMONES and triiodothyronine resin uptake (T3 up) were measured in 30 patients under dialysis and compared with 40 persons from the control group. After RENAL TRANSPLANTATION the patients were subdivided in to two group: 21 patients had optimal primary graft function (group І) and 9 patients had delayed graft function (group ІІ). All patients received maintenance therapy with prednisilone, aziothoprine and cyclosporine, and thyroid indices were measured in them.In dialysis patients thyroid-parameters were in the normal range, but compared with the control, mean levels of THYROID HORMONES were low and T3 uptake high however no changes could be observed in the levels of THYROTROPIN.Ten days after graft, reduction in the levels of THYROTROPIN and THYROID HORMONES and elevation of T3 uptake were found in both the groups. The hormone alterations in group ІІ were more than in group І. On the 30th day after graft, changes in group І reached normal levels and comparing with pregraft conditions those of before a marked improvement was noticed, but comparing with the control, the levels of free and total triiodothyronine and total thyroxine were still low.In the group ІІ, the levels of free and total thyriod hormones were lower than those of befor operation and comparing with the control, decreased levels of THYROID HORMONES and elevation in the T3 Up were observed.Our studies demonstrated that there existed a relationship between the levels of THYROID HORMONES and function of the transplanted kidney and this relationship was more significant as regards thyroxine and triiodothyronine.

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APA: Copy

HOSSEINI, E.A.S., & GHASEMZADEH, M.. (2001). THYROID HORMONE LEVELS BEFORE AND AFTER RENAL TRANSPLANTATION IN DIALYSED AND NORMAL PATIENTS AND THEIR RELATIONSHIP WITH RENAL GRAFT FUNCTION. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 19(1), 16-20. SID. https://sid.ir/paper/41464/en

Vancouver: Copy

HOSSEINI E.A.S., GHASEMZADEH M.. THYROID HORMONE LEVELS BEFORE AND AFTER RENAL TRANSPLANTATION IN DIALYSED AND NORMAL PATIENTS AND THEIR RELATIONSHIP WITH RENAL GRAFT FUNCTION. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2001;19(1):16-20. Available from: https://sid.ir/paper/41464/en

IEEE: Copy

E.A.S. HOSSEINI, and M. GHASEMZADEH, “THYROID HORMONE LEVELS BEFORE AND AFTER RENAL TRANSPLANTATION IN DIALYSED AND NORMAL PATIENTS AND THEIR RELATIONSHIP WITH RENAL GRAFT FUNCTION,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 19, no. 1, pp. 16–20, 2001, [Online]. Available: https://sid.ir/paper/41464/en

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