STUDY OF SOME PROBABLE REASONS FOR OCCURRENCE OF CONGENITAL FACIAL DYSMORPHY AND HYDROCEPHALY IN AN INFANT WITH MATERNAL HYPERTHYROIDISM AND TREATED WITH METHIMAZOLE AND PROPYL THIOURACIL

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POURJAFARI H.; HASHEMZADEH CHALESHTORI M.

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Journal: Journal of Medical Council of Iran Year:2003 | Volume:21 | Issue:3 Page(s): 228-230

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Title

STUDY OF SOME PROBABLE REASONS FOR OCCURRENCE OF CONGENITAL FACIAL DYSMORPHY AND HYDROCEPHALY IN AN INFANT WITH MATERNAL HYPERTHYROIDISM AND TREATED WITH METHIMAZOLE AND PROPYL THIOURACIL

Author(s)

POURJAFARI H. | HASHEMZADEH CHALESHTORI M. | Issue Writer Certificate

Keywords

HYPERTHYROIDISMQ3

DRUG THERAPYQ3

FACEQ3

ABNORMALITYQ3

HYDROCEPHALUSQ3

Abstract

HYPERTHYROIDISM is second to diabetes mellitus as the most common endocrinopathy in pregnancy. It has been shown that experimental HYPERTHYROIDISM in pregnant mice, produces some difficulties in their embryos. The goal of the present paper is to evaluate some probable reasons for occurrence of congenital facial dysmorphy and hydrocephaly in a Hamadanian newborn after maternal HYPERTHYROIDISM and chemotherapy.A female newborn was reported to have facial dysmorphy and hydrocephaly. She was born after a period of 8 month pregnancy by cesarean section and died after a few minutes. Her 28 year old mother was affected with HYPERTHYROIDISM and before pregnancy and also during the first two, weeks of pregnancy was treated with Methimazole After being informed of pregnancy, physician prescribed tabl Propyl thiouracil (50 mg/day). Their pedigree pattern and family history were studied and familial effect was ruled out.It seems that probably maternal HYPERTHYROIDISM and/or DRUG THERAPY was the cause (s).There are numerous evidences that show that when maternal HYPERTHYROIDISM is not under control maternal, fetal and neonatal complications are frequent.Although the role of chemotherapy and drugs in producing congenital anomalies in human beings is difficult to be established but the results of the present study reveal that pedigree pattern was not involved in producing the congenital anamoly.

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APA: Copy

POURJAFARI, H., & HASHEMZADEH CHALESHTORI, M.. (2003). STUDY OF SOME PROBABLE REASONS FOR OCCURRENCE OF CONGENITAL FACIAL DYSMORPHY AND HYDROCEPHALY IN AN INFANT WITH MATERNAL HYPERTHYROIDISM AND TREATED WITH METHIMAZOLE AND PROPYL THIOURACIL. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 21(3), 228-230. SID. https://sid.ir/paper/41470/en

Vancouver: Copy

POURJAFARI H., HASHEMZADEH CHALESHTORI M.. STUDY OF SOME PROBABLE REASONS FOR OCCURRENCE OF CONGENITAL FACIAL DYSMORPHY AND HYDROCEPHALY IN AN INFANT WITH MATERNAL HYPERTHYROIDISM AND TREATED WITH METHIMAZOLE AND PROPYL THIOURACIL. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2003;21(3):228-230. Available from: https://sid.ir/paper/41470/en

IEEE: Copy

H. POURJAFARI, and M. HASHEMZADEH CHALESHTORI, “STUDY OF SOME PROBABLE REASONS FOR OCCURRENCE OF CONGENITAL FACIAL DYSMORPHY AND HYDROCEPHALY IN AN INFANT WITH MATERNAL HYPERTHYROIDISM AND TREATED WITH METHIMAZOLE AND PROPYL THIOURACIL,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 21, no. 3, pp. 228–230, 2003, [Online]. Available: https://sid.ir/paper/41470/en

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