Models and Assessment Tes ts of the Spinal Cord Injury in Rats

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Rahmani Ghazal; Mirshekari Hamze; ZAVVARI FAHIMEH; KARIMZADEH FARIBA

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Journal: Neuroscience Journal of Shefaye Khatam Year:2020 | Volume:9 | Issue:1 Page(s): 166-188

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Title

Models and Assessment Tes ts of the Spinal Cord Injury in Rats

Author(s)

Rahmani Ghazal | Mirshekari Hamze | ZAVVARI FAHIMEH | KARIMZADEH FARIBA | Issue Writer Certificate

Keywords

Spinal Cord InjuriesQ2

Behavior Rating ScaleQ1

RatsQ2

Abstract

Introduction: Functional improvement is the major goal of therapeutic intervention in animal models of different diseases. To tes t therapeutic approaches of spinal cord injury (SCI), it is essential to produce an appropriate SCI animal model. In this model, the pathophysiological processes and his tological alterations should be similar to humans. Mos t of the mechanisms for drug effect in SCI in human and animal spinal cord seems to be similar. The main types of experimental models of SCI with various applications have been reviewed. In the next s tep, behavioral tes ts to assess Spinal Cord Injuries were mentioned. Conclusion: Choosing an appropriate SCI model is crucial for the accuracy of inves tigations. The validity of any behavioral tes t depends on the reliability, authenticity, and universality. In this article, besides the illus tration of different models and evaluating tes ts of spinal injury, selection criteria, as well as advantages and disadvantages, are discussed.

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APA: Copy

Rahmani, Ghazal, Mirshekari, Hamze, ZAVVARI, FAHIMEH, & KARIMZADEH, FARIBA. (2021). Models and Assessment Tes ts of the Spinal Cord Injury in Rats. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 9(1 ), 166-188. SID. https://sid.ir/paper/416482/en

Vancouver: Copy

Rahmani Ghazal, Mirshekari Hamze, ZAVVARI FAHIMEH, KARIMZADEH FARIBA. Models and Assessment Tes ts of the Spinal Cord Injury in Rats. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM[Internet]. 2021;9(1 ):166-188. Available from: https://sid.ir/paper/416482/en

IEEE: Copy

Ghazal Rahmani, Hamze Mirshekari, FAHIMEH ZAVVARI, and FARIBA KARIMZADEH, “Models and Assessment Tes ts of the Spinal Cord Injury in Rats,” NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, vol. 9, no. 1 , pp. 166–188, 2021, [Online]. Available: https://sid.ir/paper/416482/en

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