FREQUENCY OF HYPER- AND HYPO-NATREMIA IN PATIENTS ADMITTED IN THE ICU & COMPARISON OF THEIR ASSOCIATION WITH MORTALITY

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MOKHTARI MAJID; KOUCHAK M.; GOHARANI R.; MIRI M.M.; EGHTESADI ARAGHI P.

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Journal: Research in Medicine Year:2009 | Volume:33 | Issue:3 Page(s): 183-188

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Title

FREQUENCY OF HYPER- AND HYPO-NATREMIA IN PATIENTS ADMITTED IN THE ICU & COMPARISON OF THEIR ASSOCIATION WITH MORTALITY

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Keywords

HYPONATREMIAQ3

HYPEMATREMIAQ2

INTENSIVE CARE UNITQ2

OUTCOMEQ2

Abstract

Background: Sodium disturbances are among the most common electrolyte disturbance in INTENSIVE CARE UNIT (ICU) patients. The aim of the present study was to determine the frequency of HYPEMATREMIA, HYPONATREMIA and their comparison in relation to their mortality impact on patients admitted to a general ICU.Methods: In a cross sectional fashion we studied 273 patients hospitalized in an ICU of a large teaching hospital in Tehran, Iran between 2004 and 2006. Age, sex, reasons for hospitalization, HYPONATREMIA (serum sodium< 135 mEq/L) and HYPEMATREMIA (serum sodium> 145 mEq/L) during ICU stay were recorded and their effect son ICU mortality of the patients were assessed. Results: We observed HYPEMATREMIAin 39.5%and HYPONATREMIAin 60.5% of our patients. The mean age of patients with serum sodium imbalance was significantly higher as compared to those without it; 52±21 vs. 44±20 years for hyponatremics and 56±20vs. 49±22 years for hypematremics respectively. HYPONATREMIA occurred more frequently in surgical patients than those with medical causes, 72% vs. 22% respectively. Mortality of patients with HYPONATREMIA (34% vs. 15% with odds ratio of 5.7 and 95% CI from 2.9 to 11.30) and HYPEMATREMIA (55.2% vs. 17.8% with odds ratio of 2.8 and 95% CI from 1.4 to 5.5) were significantly higher than patients without sodium imbalance. 55% with HYPEMATREMIAdied vs. 34% with HYPONATREMIA, (95%CI from7.7%to 33.9%, p value= 0.0034).Conclusion: Serum sodium imbalances are frequent in ICU patients, occurring more frequently in older individuals and are associated with an unacceptably high mortality. Mortality was significantly higher in patients with HYPEMATREMIA compared to those with HYPONATREMIA.

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APA: Copy

MOKHTARI, MAJID, KOUCHAK, M., GOHARANI, R., MIRI, M.M., & EGHTESADI ARAGHI, P.. (2009). FREQUENCY OF HYPER- AND HYPO-NATREMIA IN PATIENTS ADMITTED IN THE ICU & COMPARISON OF THEIR ASSOCIATION WITH MORTALITY. PAJOUHESH DAR PEZESHKI, 33(3), 183-188. SID. https://sid.ir/paper/41652/en

Vancouver: Copy

MOKHTARI MAJID, KOUCHAK M., GOHARANI R., MIRI M.M., EGHTESADI ARAGHI P.. FREQUENCY OF HYPER- AND HYPO-NATREMIA IN PATIENTS ADMITTED IN THE ICU & COMPARISON OF THEIR ASSOCIATION WITH MORTALITY. PAJOUHESH DAR PEZESHKI[Internet]. 2009;33(3):183-188. Available from: https://sid.ir/paper/41652/en

IEEE: Copy

MAJID MOKHTARI, M. KOUCHAK, R. GOHARANI, M.M. MIRI, and P. EGHTESADI ARAGHI, “FREQUENCY OF HYPER- AND HYPO-NATREMIA IN PATIENTS ADMITTED IN THE ICU & COMPARISON OF THEIR ASSOCIATION WITH MORTALITY,” PAJOUHESH DAR PEZESHKI, vol. 33, no. 3, pp. 183–188, 2009, [Online]. Available: https://sid.ir/paper/41652/en

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