COMPARING ANALGETIC EFFECT OF INDOMETHACIN SUPPOSITORY AND INTRAMUSCULAR PETHIDINE IN POST CESAREAN SECTION PERIOD

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AJORI L.; ARABI F.; NEYSANI SAMANI E.; AZARGASHB E.A.; NAKHODA K.

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Journal: Research in Medicine Year:2008 | Volume:32 | Issue:1 Page(s): 55-59

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Title

COMPARING ANALGETIC EFFECT OF INDOMETHACIN SUPPOSITORY AND INTRAMUSCULAR PETHIDINE IN POST CESAREAN SECTION PERIOD

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Keywords

INDOMETHACIN SUPPOSITORYQ3

CESAREAN SECTIONQ3

PETHIDINEQ3

Abstract

Background: Although postoperative pain has been suitably controlled by new analgetic agents, it is still a major health concern following the operation. The present study was designed to compare the analgetic effect of INDOMETHACIN SUPPOSITORY and intramuscular PETHIDINE in post CESAREAN SECTION period. Materials and methods: For this randomized controlled clinical trial, 204 women subjected for elective or emergency CESAREAN SECTION were enrolled. They were randomly assigned in 3 groups; INDOMETHACIN SUPPOSITORY 200mg (68 subjects), intramuscular PETHIDINE 50mg (68 subjects), and placebo (68 subjects). Response to therapy was assessed by Visual Analog Scale (VAS) during the first hour and 8 hours following the second and third dose. Results: Results revealed a significant pain relief following the first and second dose of indomethacin when compared with placebo and PETHIDINE groups (p<0.05). Meanwhile, pain was significantly relieved 4 hours following the first and second dose of PETHIDINE when compared with placebo; however, the effect was even greater 8 hours later. Conclusions: INDOMETHACIN SUPPOSITORY could effectively relieve pain during the first day following the CESAREAN SECTION.

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APA: Copy

AJORI, L., ARABI, F., NEYSANI SAMANI, E., AZARGASHB, E.A., & NAKHODA, K.. (2008). COMPARING ANALGETIC EFFECT OF INDOMETHACIN SUPPOSITORY AND INTRAMUSCULAR PETHIDINE IN POST CESAREAN SECTION PERIOD. PAJOUHESH DAR PEZESHKI, 32(1), 55-59. SID. https://sid.ir/paper/41872/en

Vancouver: Copy

AJORI L., ARABI F., NEYSANI SAMANI E., AZARGASHB E.A., NAKHODA K.. COMPARING ANALGETIC EFFECT OF INDOMETHACIN SUPPOSITORY AND INTRAMUSCULAR PETHIDINE IN POST CESAREAN SECTION PERIOD. PAJOUHESH DAR PEZESHKI[Internet]. 2008;32(1):55-59. Available from: https://sid.ir/paper/41872/en

IEEE: Copy

L. AJORI, F. ARABI, E. NEYSANI SAMANI, E.A. AZARGASHB, and K. NAKHODA, “COMPARING ANALGETIC EFFECT OF INDOMETHACIN SUPPOSITORY AND INTRAMUSCULAR PETHIDINE IN POST CESAREAN SECTION PERIOD,” PAJOUHESH DAR PEZESHKI, vol. 32, no. 1, pp. 55–59, 2008, [Online]. Available: https://sid.ir/paper/41872/en

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