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Information Journal Paper

Title

CONJUGATED LINOLEIC ACID AND LIPID PROFILE OF POSTMENOPAUSAL WOMEN

Pages

  26-34

Abstract

 Background: Most animal studies have shown that trans-10 and cis-12 isomers of CONJUGATED LINOLEIC ACID, (CLA) tend to increase INSULIN RESISTANCE. But the effect of equal isomers of CLA (50: 50 ratios of cis-9, trans-11: trans-10, cis-12 isomers) on LIPID PROFILEs, glucose, and INSULIN RESISTANCE and sensitivity in POSTMENOPAUSAL WOMEN is not clear.Methods: In the present study, we performed a randomized, double blind, placebo-controlled trial to examine the changes in LIPID PROFILEs, glucose, and insulin concentration following 4 CLAG80 capsules containing 3.2g CLA (50: 50 ratios of cis-9, trans-11: trans-10, cis-12 isomers) or 4 placebo capsules supplementation for 12 weeks in post-menopausal women. Seventy six healthy post-menopausal women were randomized to receive placebo or 3.2 g CLA for 12 weeks. Anthropometric measurements were done. Blood samples were collected after 12-14 hours fasting before and after intervention. INSULIN RESISTANCE and insulin sensitivity were estimated based on the homeostasis (HOMA) and QUIKI models. In weeks 0, 6 and 12 during the trial, subjects completed 3d dietary records. These dietary records were coded by the same dietitian, and analyzed with the Food Processor program. Result: There were no significant effect on serum lipids, insulin, glucose, INSULIN RESISTANCE and insulin sensitivity over 12 weeks in POSTMENOPAUSAL WOMEN.Conclusion: Mixed isomer CLA supplementation had no effect on serum insulin, lipids profile, glucose and INSULIN RESISTANCE/sensitivity during 12 weeks of intervention in POSTMENOPAUSAL WOMEN.

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    APA: Copy

    TAVAKKOLI DARESTANI, AZADEH, HOSSEINPANAH, FARHAD, HEDAYATI, MEHDI, AMIRI, ZOHREH, TAVAKKOLI DARESTANI, REZA, & TAHBAZ, FARIDEH. (2010). CONJUGATED LINOLEIC ACID AND LIPID PROFILE OF POSTMENOPAUSAL WOMEN. PAJOUHESH DAR PEZESHKI, 34(1), 26-34. SID. https://sid.ir/paper/41906/en

    Vancouver: Copy

    TAVAKKOLI DARESTANI AZADEH, HOSSEINPANAH FARHAD, HEDAYATI MEHDI, AMIRI ZOHREH, TAVAKKOLI DARESTANI REZA, TAHBAZ FARIDEH. CONJUGATED LINOLEIC ACID AND LIPID PROFILE OF POSTMENOPAUSAL WOMEN. PAJOUHESH DAR PEZESHKI[Internet]. 2010;34(1):26-34. Available from: https://sid.ir/paper/41906/en

    IEEE: Copy

    AZADEH TAVAKKOLI DARESTANI, FARHAD HOSSEINPANAH, MEHDI HEDAYATI, ZOHREH AMIRI, REZA TAVAKKOLI DARESTANI, and FARIDEH TAHBAZ, “CONJUGATED LINOLEIC ACID AND LIPID PROFILE OF POSTMENOPAUSAL WOMEN,” PAJOUHESH DAR PEZESHKI, vol. 34, no. 1, pp. 26–34, 2010, [Online]. Available: https://sid.ir/paper/41906/en

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