INVESTIGATION OF THE THICKNESS OF THE RETINAL NERVE FIBER IN MULTIPLE SCLEROSIS RECURRING-RECOVERY: A LONGITUDINAL STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Mirmosayyeb Omid; MMANOUCHEHRI NAVID; TOGHIANI NAFISE; DEHGHANI ALIREZA; GOLABCHI KHODAYAR; DEHGHANI LEYLA; BADIHIAN SHERVIN; FAYYAZI EMAD; SHAYGANNEJAD VAHID

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Research in Medicine Year:2018 | Volume:42 | Issue:2 Page(s): 106-109

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

781

Download:

Cites:

Information Journal Paper

Title

INVESTIGATION OF THE THICKNESS OF THE RETINAL NERVE FIBER IN MULTIPLE SCLEROSIS RECURRING-RECOVERY: A LONGITUDINAL STUDY

Author(s)

Keywords

RETINAL NERVE FIBER LAYERQ1

THICKNESS DECREASESQ1

MULTIPLE SCLEROSISQ2

Abstract

Background: The previous studies suggest that RETINAL NERVE FIBER LAYER (RNFL) THICKNESS DECREASES over time in MULTIPLE SCLEROSIS (MS) and can be a marker of disease activity for patients’ follow-up. Here, we aimed to compare RNFL thickness in patients with Relapsing Remitting MS (RRMS) during three years of follow-up.Methods: In the present prospective study, patients with diagnosis of RRMS and history of optic neuritis were included.Demographic features and disease characteristics were collected and underwent Optical Coherence Tomography (OCT). OCT was repeated after three years and the obtained values were compared.Results: A total of 12 patients (11 women) with the mean age of 35.6 ± 6.1 years and mean disease duration of 5.3 ± 5.8 were included in the study. RNFL thicknesses were 101.27 ± 9.15 mm and 92.00 ±7.96 mm in the left eye at the baseline and after 3 years, respectively (P-value<0.001). In the right eye, RNFL thicknesses were 99.72 ± 16.37 mm and 86.36 ± 20.35 mm at the baseline and after 3 years, respectively (p=0.014).Conclusions: We found a significant decrease in RNFL thickness in RRMS patients after 3 years of follow up, in spite of getting immunomodulatory treatment. We recommend OCT as an inexpensive and feasible tool for outcome measurement in RRMS patients.

Cites

No record.

References

Evaluating the effect of adding Fish oil to Fingolimod on TNF-alpha, IL1beta, IL6, and IFN-gamma in patients with relapsing-remitting multiple sclerosis: A double-blind randomized placebocontrolled trial

Cite

APA: Copy

Mirmosayyeb, Omid, MMANOUCHEHRI, NAVID, TOGHIANI, NAFISE, DEHGHANI, ALIREZA, GOLABCHI, KHODAYAR, DEHGHANI, LEYLA, BADIHIAN, SHERVIN, FAYYAZI, EMAD, & SHAYGANNEJAD, VAHID. (2018). INVESTIGATION OF THE THICKNESS OF THE RETINAL NERVE FIBER IN MULTIPLE SCLEROSIS RECURRING-RECOVERY: A LONGITUDINAL STUDY. PAJOUHESH DAR PEZESHKI, 42(2 ), 106-109. SID. https://sid.ir/paper/41971/en

Vancouver: Copy

Mirmosayyeb Omid, MMANOUCHEHRI NAVID, TOGHIANI NAFISE, DEHGHANI ALIREZA, GOLABCHI KHODAYAR, DEHGHANI LEYLA, BADIHIAN SHERVIN, FAYYAZI EMAD, SHAYGANNEJAD VAHID. INVESTIGATION OF THE THICKNESS OF THE RETINAL NERVE FIBER IN MULTIPLE SCLEROSIS RECURRING-RECOVERY: A LONGITUDINAL STUDY. PAJOUHESH DAR PEZESHKI[Internet]. 2018;42(2 ):106-109. Available from: https://sid.ir/paper/41971/en

IEEE: Copy

Omid Mirmosayyeb, NAVID MMANOUCHEHRI, NAFISE TOGHIANI, ALIREZA DEHGHANI, KHODAYAR GOLABCHI, LEYLA DEHGHANI, SHERVIN BADIHIAN, EMAD FAYYAZI, and VAHID SHAYGANNEJAD, “INVESTIGATION OF THE THICKNESS OF THE RETINAL NERVE FIBER IN MULTIPLE SCLEROSIS RECURRING-RECOVERY: A LONGITUDINAL STUDY,” PAJOUHESH DAR PEZESHKI, vol. 42, no. 2 , pp. 106–109, 2018, [Online]. Available: https://sid.ir/paper/41971/en

Related Journal Papers