A REPORT OF DIAGNOSIS AND TREATMENT LEVELS OF 18 PANCREATIC INSULINOMA PATIENTS AT TALEGHANI HOSPITAL AND PROVIDING A TREATMENT ALGORITHM FOR THIS DISEASE

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MOGHIMI MEHRDAD; YAVARI ALI; PEYRAVI HABIBOLLAH; EYVAZI KAHRANE FARIBA; NEJATOLAHI MOHAMMADREZA; YAVARI MOHAMMAD

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Journal: Research in Medicine Year:2016 | Volume:40 | Issue:2 Page(s): 58-63

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Title

A REPORT OF DIAGNOSIS AND TREATMENT LEVELS OF 18 PANCREATIC INSULINOMA PATIENTS AT TALEGHANI HOSPITAL AND PROVIDING A TREATMENT ALGORITHM FOR THIS DISEASE

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Keywords

INSULINOMAQ3

LOCALIZATIONQ1

ALGORITHMQ2

Abstract

Background: INSULINOMA tumor is the most common endocrine tumor of pancreas and is diagnosed by clinical symptoms (whipple’s triad) and paraclinical laboratory test results. Surgery is the main treatment. Optimum utilization of tumor LOCALIZATION techniques can minimize the loss of surgery complications and outcome of surgery in these patients. Aim of this study was to evaluate the diagnostic power of tumor LOCALIZATION by radiologic methods and surgeon palpation and compare these methods to propose useful recommendations for treatment of patients. Finally, we want to propose a diagnostic ALGORITHMic approach according to available radiologic tools in our country.Method and materials: First, referral suspicious INSULINOMA patients from endocrinology ward of Taleghani hospital studied with CT scan and endosonography to localize tumor and then they are transferred to OR for surgery. After exploration of pancreas during surgery, pancreas is palpated exactly by experienced surgeon to localize tumor and findings are registered, then intraoperative sonography is completed and again findings are registered. Then appropriate surgery according to our study (pancreatectomy or enucleation) is done. After surgery we followed patients checking BS and pathology report. Finally, we calculated the power of the mentioned methods in LOCALIZATION of INSULINOMA tumor in comparison with pathology report as a gold standard.Results: Positive predictive value of CT scan, endosonography, intraoperative sonography and surgeon palpation in order was %85.7, %92.3, %83.3 and %83.3 and the negative predictive value of CT scan, endosonography, intraoperative sonography and surgeon palpation in order was %66.6, %75, %27.2 and %40.Conclusion: CT scan did not help in diagnosis and treatment of patients in presence of other LOCALIZATION methods. Endosonography in this study had the highest accuracy. Finally, recommended diagnostic ALGORITHMic approach seems to be useful in treatment of INSULINOMA patients. The diagnostic power of this ALGORITHMic approach needs more evaluation.

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APA: Copy

MOGHIMI, MEHRDAD, YAVARI, ALI, PEYRAVI, HABIBOLLAH, EYVAZI KAHRANE, FARIBA, NEJATOLAHI, MOHAMMADREZA, & YAVARI, MOHAMMAD. (2016). A REPORT OF DIAGNOSIS AND TREATMENT LEVELS OF 18 PANCREATIC INSULINOMA PATIENTS AT TALEGHANI HOSPITAL AND PROVIDING A TREATMENT ALGORITHM FOR THIS DISEASE. PAJOUHESH DAR PEZESHKI, 40(2 ), 58-63. SID. https://sid.ir/paper/42063/en

Vancouver: Copy

MOGHIMI MEHRDAD, YAVARI ALI, PEYRAVI HABIBOLLAH, EYVAZI KAHRANE FARIBA, NEJATOLAHI MOHAMMADREZA, YAVARI MOHAMMAD. A REPORT OF DIAGNOSIS AND TREATMENT LEVELS OF 18 PANCREATIC INSULINOMA PATIENTS AT TALEGHANI HOSPITAL AND PROVIDING A TREATMENT ALGORITHM FOR THIS DISEASE. PAJOUHESH DAR PEZESHKI[Internet]. 2016;40(2 ):58-63. Available from: https://sid.ir/paper/42063/en

IEEE: Copy

MEHRDAD MOGHIMI, ALI YAVARI, HABIBOLLAH PEYRAVI, FARIBA EYVAZI KAHRANE, MOHAMMADREZA NEJATOLAHI, and MOHAMMAD YAVARI, “A REPORT OF DIAGNOSIS AND TREATMENT LEVELS OF 18 PANCREATIC INSULINOMA PATIENTS AT TALEGHANI HOSPITAL AND PROVIDING A TREATMENT ALGORITHM FOR THIS DISEASE,” PAJOUHESH DAR PEZESHKI, vol. 40, no. 2 , pp. 58–63, 2016, [Online]. Available: https://sid.ir/paper/42063/en

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