CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY AFTER PHOTOREFRACTIVE KERATECTOMY WITH MITOMYCIN C

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JAFARINASAB M.R.; FEIZI S.; ZAMANI M.; JABARPOOR BONYADI M.H.; YASERI M.

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Journal: BINA Year:2011 | Volume:17 | Issue:1 (66) Page(s): 3-7

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Title

CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY AFTER PHOTOREFRACTIVE KERATECTOMY WITH MITOMYCIN C

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Keywords

PHOTOREFRACTIVE KERATECTOMYQ3

MYOPIAQ3

MITOMYCIN CQ3

CORNEAL ENDOTHELIAL CELL LOSSQ3

Abstract

Purpose: To assess the short-term effect of Mitomycin-C (MMC) 0.02% on endothelial cell density and morphology after PHOTOREFRACTIVE KERATECTOMY (PRK) in patients with moderate MYOPIA.Methods: Forty-two eyes of 21 participants with moderate MYOPIA (range, -4.0 to -8.0 D) underwent PRK with MMC 0.02% for 40 seconds. Specular microscopy was performed preoperatively and repeated 6 months after surgery to determine any change in central endothelial cell density (ECD), mean cell area (MCA), and coefficient of variation in cell size (CV).Results: Mean patient age was 26.2±6.3. Mean preoperative spherical equivalent refractive error was -5.2±1.2 D which was reduced to -0.4±0.5 D postoperatively (P<0.001). Mean ECD was reduced insignificantly from2920±363 cells/mm2 preoperatively to 2802±339 cells/mm2 postoperatively (P=0.59). Similarly, there was no significant change in MCA (P=0.76) or CV (P=0.52) at six months.Conclusion: Intraoperative MMC 0.02% applied for 40 seconds during PRK for moderate MYOPIA did not significantly change central corneal endothelial cell density and morphology after 6 months.

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APA: Copy

JAFARINASAB, M.R., FEIZI, S., ZAMANI, M., JABARPOOR BONYADI, M.H., & YASERI, M.. (2011). CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY AFTER PHOTOREFRACTIVE KERATECTOMY WITH MITOMYCIN C. BINA, 17(1 (66)), 3-7. SID. https://sid.ir/paper/42225/en

Vancouver: Copy

JAFARINASAB M.R., FEIZI S., ZAMANI M., JABARPOOR BONYADI M.H., YASERI M.. CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY AFTER PHOTOREFRACTIVE KERATECTOMY WITH MITOMYCIN C. BINA[Internet]. 2011;17(1 (66)):3-7. Available from: https://sid.ir/paper/42225/en

IEEE: Copy

M.R. JAFARINASAB, S. FEIZI, M. ZAMANI, M.H. JABARPOOR BONYADI, and M. YASERI, “CORNEAL ENDOTHELIAL CELL DENSITY AND MORPHOLOGY AFTER PHOTOREFRACTIVE KERATECTOMY WITH MITOMYCIN C,” BINA, vol. 17, no. 1 (66), pp. 3–7, 2011, [Online]. Available: https://sid.ir/paper/42225/en

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