TNF-ALPHA GENE POLYMORPHISMS IN PATIENTS WITH BEHCET'S DISEASE AND OCULAR INVOLVMENT IN AN IRANIAN AZERI POPULATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JABARPOUR BONYADI MORTEZA; JABARPOUR BONIAADI MOHAMMAD HOSSEIN; JAHANAFROUZ Z.; KOLAHI S.; DASTGIRI S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: BINA Year:2010 | Volume:16 | Issue:1 (62) Page(s): 35-41

Download Full-Text

Persian Verion

View:

840

Download:

Cites:

Information Journal Paper

Title

TNF-ALPHA GENE POLYMORPHISMS IN PATIENTS WITH BEHCET'S DISEASE AND OCULAR INVOLVMENT IN AN IRANIAN AZERI POPULATION

Author(s)

Keywords

TNF-ALPHAQ3

POLYMORPHISMQ3

BEHCET'S DISEASEQ3

Abstract

Purpose: To evaluate the distribution of TNF-ALPHA promoter -1031T/C and -308G/A POLYMORPHISMs in an Iranian population with Behcet disease and ocular manifestation.Method: We investigated the distribution of TNF-ALPHA promoter -1031T/C and -308G/A POLYMORPHISMs in 53 patients with Behcet disease (BD) and 79 matched healthy controls, using the PCR-RFLP technique. All subjects were from an Iranian Azeri population.Results: The frequency of the TNF-ALPHA -308G/A POLYMORPHISM was similar in BD patients and healthy controls (P= 0.234) whereas the frequency of the TNF-ALPHA-1031T/C POLYMORPHISM was different between two groups (P= 0.0006). The frequency of the CG haplotype was significantly higher (P< 0.0001), and that of the TA haplotype was significantly lower in BD patients than healthy controls. Different TNF-a-1031T/C and TNF-a-308G/A POLYMORPHISMs were not associated with ocular involvement.Conclusion: TNF-ALPHA is a susceptibility gene for BD in Iranian patients of Azeri ethnicity. There was no relation between different haplotypes in the investigated genetic region in this group of BD patients with ocular manifestation.

Cites

No record.

References

No record.

Cite

APA: Copy

JABARPOUR BONYADI, MORTEZA, JABARPOUR BONIAADI, MOHAMMAD HOSSEIN, JAHANAFROUZ, Z., KOLAHI, S., & DASTGIRI, S.. (2010). TNF-ALPHA GENE POLYMORPHISMS IN PATIENTS WITH BEHCET'S DISEASE AND OCULAR INVOLVMENT IN AN IRANIAN AZERI POPULATION. BINA, 16(1 (62)), 35-41. SID. https://sid.ir/paper/42587/en

Vancouver: Copy

JABARPOUR BONYADI MORTEZA, JABARPOUR BONIAADI MOHAMMAD HOSSEIN, JAHANAFROUZ Z., KOLAHI S., DASTGIRI S.. TNF-ALPHA GENE POLYMORPHISMS IN PATIENTS WITH BEHCET'S DISEASE AND OCULAR INVOLVMENT IN AN IRANIAN AZERI POPULATION. BINA[Internet]. 2010;16(1 (62)):35-41. Available from: https://sid.ir/paper/42587/en

IEEE: Copy

MORTEZA JABARPOUR BONYADI, MOHAMMAD HOSSEIN JABARPOUR BONIAADI, Z. JAHANAFROUZ, S. KOLAHI, and S. DASTGIRI, “TNF-ALPHA GENE POLYMORPHISMS IN PATIENTS WITH BEHCET'S DISEASE AND OCULAR INVOLVMENT IN AN IRANIAN AZERI POPULATION,” BINA, vol. 16, no. 1 (62), pp. 35–41, 2010, [Online]. Available: https://sid.ir/paper/42587/en

Related Journal Papers