Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

874
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

THREE INTRAVITREAL BEVACIZUMAB VERSUS TWO INTRAVITREAL TRIAMCINOLONE INJECTIONS IN RECENT ONSET BRANCH RETINAL VEIN OCCLUSION

Pages

  156-168

Abstract

 Purpose: To compare repeated intravitreal injections of bevacizumab (IVB) with triamcinolone acetonide (IVT) for treatment of acute RETINAL VEIN OCCLUSION/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">BRANCH RETINAL VEIN OCCLUSION (BRVO).Methods: This randomized clinical trial included, 86 eyes with recent onset (less than 12 weeks) BRVO. Participants were randomly assigned to two treatment groups: the IVB group (43 eyes) consisted of patients who received monthly injections of 1.25 mg IVB, and the IVT group (43 eyes) comprised of patients who received 2 injections of 2 mg IVT two months apart. Patients were examined 1, 2, 3, 4, and 6 months after enrollment. The main outcome measure was change in best-corrected visual acuity (BCVA) at 6 months. Secondary outcome measures were central macular thickness (CMT) and intraocular pressure (IOP) changes at month 6.Results: Mean BCVA improved significantly up to 6 months in both groups from 0.25±0.68 to 0.31±0.21 LogMAR (logarithm of minimum angle of resolution) in the IVB group, and from 0.67±0.29 to 0.46±0.31 LogMAR in the IVT group, (P<0.001 for both groups). However, inter-group differences reached significant levels at months 4 (P=0.013) and 6 (P<0.001) in favor of the IVB group. In terms of CMT reduction, similarly, both groups showed a significant decrease at months 3 and 6, and the differences between the groups was statistically significant (P=0.031) at final visit. Dividing the cases into ischemic and non-ischemic types, a significant difference was noted only in ischemic cases regarding BCVA improvement and CMT reduction in favor of the IVB group. Mean IOP rise was significantly higher in the IVT group at all visits.Conclusion: Both 3 times monthly IVB injections and 2 times IVT injections with two month interval could be effective for improving BCVA and CMT in cases with recent onset BRVO up to 6 months. However, considering the better visual and anatomic outcomes after IVB injections and the potential complications of IVT injections, we would recommend prescheduled repeated IVB injections for such cases. The favorable responses were more pronounced in the ischemic types of BRVO in this trial; nevertheless, this should be confirmed in larger studies.

Cites

  • No record.
  • References

  • No record.
  • Cite

    APA: Copy

    RAMEZANI, A., ESFANDIARI, H., ENTEZARI, M., MORADIAN, S., SOHEILIAN, M., FEIZI, M., & YASERI, M.. (2013). THREE INTRAVITREAL BEVACIZUMAB VERSUS TWO INTRAVITREAL TRIAMCINOLONE INJECTIONS IN RECENT ONSET BRANCH RETINAL VEIN OCCLUSION. BINA, 18(2 (71)), 156-168. SID. https://sid.ir/paper/42958/en

    Vancouver: Copy

    RAMEZANI A., ESFANDIARI H., ENTEZARI M., MORADIAN S., SOHEILIAN M., FEIZI M., YASERI M.. THREE INTRAVITREAL BEVACIZUMAB VERSUS TWO INTRAVITREAL TRIAMCINOLONE INJECTIONS IN RECENT ONSET BRANCH RETINAL VEIN OCCLUSION. BINA[Internet]. 2013;18(2 (71)):156-168. Available from: https://sid.ir/paper/42958/en

    IEEE: Copy

    A. RAMEZANI, H. ESFANDIARI, M. ENTEZARI, S. MORADIAN, M. SOHEILIAN, M. FEIZI, and M. YASERI, “THREE INTRAVITREAL BEVACIZUMAB VERSUS TWO INTRAVITREAL TRIAMCINOLONE INJECTIONS IN RECENT ONSET BRANCH RETINAL VEIN OCCLUSION,” BINA, vol. 18, no. 2 (71), pp. 156–168, 2013, [Online]. Available: https://sid.ir/paper/42958/en

    Related Journal Papers

    Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    Move to top