THE EFFECT OF RISPERIDONE ON COGNITIVE SYMPTOMS OF SCHIZOPHRENIA: A COMPARISON WITH HALOPERIDOL

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DANESHMAND R.; MAZINANI R.; FADAEI FARBOD

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Journal: Journal of Mazandaran University of Medical Sciences Year:2007 | Volume:17 | Issue:59 Page(s): 1-10

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Title

THE EFFECT OF RISPERIDONE ON COGNITIVE SYMPTOMS OF SCHIZOPHRENIA: A COMPARISON WITH HALOPERIDOL

Author(s)

DANESHMAND R. | MAZINANI R. | FADAEI FARBOD | Issue Writer Certificate

Keywords

RISPERIDONEQ3

HALOPERIDOLQ3

COGNITIVE SYMPTOMSQ3

Abstract

Background and purpose: Several studies have demonstrated that atypical antipsychotic attenuate COGNITIVE SYMPTOMS of schizophrenia more than first generation of antipsychotic. Because there was no comprehensive and reliable study on evaluating these effects in Iranian population, the research group decided to compare the effects of HALOPERIDOL and RISPERIDONE, both Iranian drug laboratories' products, on the COGNITIVE SYMPTOMS of patients with schizophrenia.Materials and Methods: 66 patients with the diagnosis of schizophrenia, according to DSM-IVTR criteria, who were hospitalized in Razi's Psychiatric Center, Tehran, were included in the study. After 2 weeks of wash-out period, patients were randomized in two groups, treated with HALOPERIDOL and RISPERIDONE, and in 8 week period basic and weekly MMSE were performed for all.Results: Both drugs improved COGNITIVE SYMPTOMS of patients, and the course of improvement started in the 2nd week of treatment with no significant statistical difference.Conclusion: The study didn't confirm the preferentiality of RISPERIDONE vs. HALOPERIDOL on the COGNITIVE SYMPTOMS of schizophrenia, which was demonstrated in western articles. Therefore, choosing each drug for treating patients must fulfill on other goals, such as the profile of their side effects.

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پیگیری درمان بیماران روانی مزمن

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APA: Copy

DANESHMAND, R., MAZINANI, R., & FADAEI, FARBOD. (2007). THE EFFECT OF RISPERIDONE ON COGNITIVE SYMPTOMS OF SCHIZOPHRENIA: A COMPARISON WITH HALOPERIDOL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 17(59), 1-10. SID. https://sid.ir/paper/44244/en

Vancouver: Copy

DANESHMAND R., MAZINANI R., FADAEI FARBOD. THE EFFECT OF RISPERIDONE ON COGNITIVE SYMPTOMS OF SCHIZOPHRENIA: A COMPARISON WITH HALOPERIDOL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;17(59):1-10. Available from: https://sid.ir/paper/44244/en

IEEE: Copy

R. DANESHMAND, R. MAZINANI, and FARBOD FADAEI, “THE EFFECT OF RISPERIDONE ON COGNITIVE SYMPTOMS OF SCHIZOPHRENIA: A COMPARISON WITH HALOPERIDOL,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 59, pp. 1–10, 2007, [Online]. Available: https://sid.ir/paper/44244/en

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