THE EFFECTS OF PROPOFOL ON TRANSURETHRAL LITHOTRIPSY

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FIROUZIAN ABOLFAZL; EMADI SEYED ABDOLLAH; ZAMANI KIASARI ALIEH; GHOLIPOUR BARADARI AFSHIN; BARZEGARNEZHAD AYYOUB; FAZLI MEHRAN; MONTAZAMI MARYAM; DANESHIAN MARYAM; SADEGHIAN MAEDEH

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Journal: Journal of Mazandaran University of Medical Sciences Year:2016 | Volume:26 | Issue:139 Page(s): 10-17

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Title

THE EFFECTS OF PROPOFOL ON TRANSURETHRAL LITHOTRIPSY

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Keywords

RENAL COLICQ2

PROPOFOLQ3

TRANSURETHRAL LITHOTRIPSY (TUL)Q3

Abstract

Background and purpose: Despite the proven effectiveness of PROPOFOL on reducing smooth muscle tone, the effect of this drug on ureteral spasm has not been investigated yet. This study was designed to investigate the effect of PROPOFOL on transurethral lithotripsy (TUL) and its influence on reducing acute ureteral spasm.Materials and methods: A double-blind clinical trial was conducted in 122 patients. Initially, all patients were given 0.02mg/kg midazolam and 2mg/kg fentanyl. The subjects were then randomly divided into two groups. The first group (n=65) received 2.5mg/kg PROPOFOL and for the second group (n=57) 5mg/kg thiopental was injected. TUL was performed using pneumatic method. Duration of TUL, hemodynamic condition, and success rate of lithotripsy, using ESWL, ureteral stent, Double J and any complications were recorded.Results: There were no significant differences in terms of gender, age, weight and stone size between the two groups (P>0.05). Duration of TUL (P=0.004) and the mean of SBP, DBP and HR in one and five minutes were significantly lower in the PROPOFOL group (P<0.01). The success rate of TUL was 96.9% and 89.5% in PROPOFOL and thiopental groups, respectively (P=0.097). Stent and double J replacement were observed in 17.5% and 22.8% of thiopental group and 20% and 16.9% of the PROPOFOL group, respectively (P=0.415).Conclusion: PROPOFOL was associated with higher reduction in systolic and diastolic blood pressure, less changes in heart rate, reducing the duration of TUL, increasing the success rate of TUL, and less need to Double J and ESWL.

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APA: Copy

FIROUZIAN, ABOLFAZL, EMADI, SEYED ABDOLLAH, ZAMANI KIASARI, ALIEH, GHOLIPOUR BARADARI, AFSHIN, BARZEGARNEZHAD, AYYOUB, FAZLI, MEHRAN, MONTAZAMI, MARYAM, DANESHIAN, MARYAM, & SADEGHIAN, MAEDEH. (2016). THE EFFECTS OF PROPOFOL ON TRANSURETHRAL LITHOTRIPSY. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 26(139), 10-17. SID. https://sid.ir/paper/44809/en

Vancouver: Copy

FIROUZIAN ABOLFAZL, EMADI SEYED ABDOLLAH, ZAMANI KIASARI ALIEH, GHOLIPOUR BARADARI AFSHIN, BARZEGARNEZHAD AYYOUB, FAZLI MEHRAN, MONTAZAMI MARYAM, DANESHIAN MARYAM, SADEGHIAN MAEDEH. THE EFFECTS OF PROPOFOL ON TRANSURETHRAL LITHOTRIPSY. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;26(139):10-17. Available from: https://sid.ir/paper/44809/en

IEEE: Copy

ABOLFAZL FIROUZIAN, SEYED ABDOLLAH EMADI, ALIEH ZAMANI KIASARI, AFSHIN GHOLIPOUR BARADARI, AYYOUB BARZEGARNEZHAD, MEHRAN FAZLI, MARYAM MONTAZAMI, MARYAM DANESHIAN, and MAEDEH SADEGHIAN, “THE EFFECTS OF PROPOFOL ON TRANSURETHRAL LITHOTRIPSY,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 139, pp. 10–17, 2016, [Online]. Available: https://sid.ir/paper/44809/en

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