RELATIONSHIP OF SERUM CERULOPLASMIN AND PRE-ECLAMPSIA

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GALINI MOGHADAM T.; MOSLEMIZADEH N.; MOHAMMADPOUR R.A.; HAMZEH ROBATI M.

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Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2008 | Volume:18 | Issue:65 Page(s): 34-41

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Title

RELATIONSHIP OF SERUM CERULOPLASMIN AND PRE-ECLAMPSIA

Author(s)

GALINI MOGHADAM T. | MOSLEMIZADEH N. | MOHAMMADPOUR R.A. | HAMZEH ROBATI M. | Issue Writer Certificate

Keywords

CERULOPLASMINQ3

PRE-ECLAMPSIAQ3

PREGNANCYQ2

Abstract

Background and Purpose: PRE-ECLAMPSIA is a PREGNANCY disorder which increases maternal and pre-natal morbidity and mortality. The incidence is about 5% and is influenced by pariety, genetic background, and environmental factors. At present, the sole treatment is termination. It is suitable to use antioxidants for PRE-ECLAMPSIA prevention. The aim of this study is to measure the maternal serum CERULOPLASMIN and evaluation of changes presented in pre-eclamptic women VS. Non pre-eclamptic ones.Materials and Methods: This study is executed in a case-control method. 100 cases were selected through pregnant women bedridden from obstetrics-gynecologic and maternity ward of Imam Khomeini Hospital in Sari. After examination of exclusion criteria in each case and receiving consent, information was entered in the questionnaire. Venous blood samples were sent to laboratory to measure CERULOPLASMIN. Data was analyzed by independent t-test.Results: The gestational age means in case and control groups were serially 36.01±2.90 and 37.86±2.82 weeks. The mean for systolic blood pressure for these two groups were serially 153.40±12.22 and 112.5±8.90 mm Hg. The average amount of serum CERULOPLASMIN in case group was significantly more than control group. 63.3% of women in the case group were in early pre-eclamptic phase and 36.7% of them were in late phase. 22% of women in this group had a history of PRE-ECLAMPSIA in previous pregnancies and 16% additionally had a history of hypertension before PREGNANCY. 92% of women in the case group had an extra normal serum CERULOPLASMIN, while in the control group the number was42%.Conclusion: The variables of Body mass Index, Systolic and Diastolic blood pressure and CERULOPLASMIN showed a significant difference between case and control groups. The history of preeclampsia and hypertension were effective on the appearance of PRE-ECLAMPSIA and increased in serum CERULOPLASMIN, can be considered as an early sign, while having a correlation with PRE-ECLAMPSIA severity.

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APA: Copy

GALINI MOGHADAM, T., MOSLEMIZADEH, N., MOHAMMADPOUR, R.A., & HAMZEH ROBATI, M.. (2008). RELATIONSHIP OF SERUM CERULOPLASMIN AND PRE-ECLAMPSIA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 18(65), 34-41. SID. https://sid.ir/paper/45142/en

Vancouver: Copy

GALINI MOGHADAM T., MOSLEMIZADEH N., MOHAMMADPOUR R.A., HAMZEH ROBATI M.. RELATIONSHIP OF SERUM CERULOPLASMIN AND PRE-ECLAMPSIA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;18(65):34-41. Available from: https://sid.ir/paper/45142/en

IEEE: Copy

T. GALINI MOGHADAM, N. MOSLEMIZADEH, R.A. MOHAMMADPOUR, and M. HAMZEH ROBATI, “RELATIONSHIP OF SERUM CERULOPLASMIN AND PRE-ECLAMPSIA,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 65, pp. 34–41, 2008, [Online]. Available: https://sid.ir/paper/45142/en

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