ASSOCIATION BETWEEN GESTATIONAL DIABETES MELLITUS AND SPONTANEOUS ABORTION: A SYSTEMATIC REVIEW AND META-ANALYSIS

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MOOSAZADEH MAHMOOD; BANAKAR MORTEZA; BEHBAHANI DARIUSH; AKBARI MARYAM; DABBAGH MANESH MOHAMMAD HOSEIN; MOHAMADKHANI MINOO; TABRIZI REZA

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2017 | Volume:27 | Issue:155 Page(s): 187-195

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Title

ASSOCIATION BETWEEN GESTATIONAL DIABETES MELLITUS AND SPONTANEOUS ABORTION: A SYSTEMATIC REVIEW AND META-ANALYSIS

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Keywords

GESTATIONAL DIABETESQ2

SPONTANEOUS ABORTIONQ3

META-ANALYSISQ3

Abstract

Background and purpose: Contradictory evidences indicate that GESTATIONAL DIABETES mellitus (GDM) increase the risk of SPONTANEOUS ABORTION (SA). Therefore, in a systematic review and metaanalysis we investigated the association between GDM and SA.Materials and methods: Relevant articles published between January 2000 and April 2016 were identified by a systematic search in national and international databases. Eligible studies were included in META-ANALYSIS after quality assessment. We also determined the heterogenic index using Cochran’s test (Q) and I2. Based on the heterogenetic results, a random effect model was performed to combine the results. Stata software was used for data analyses.Results: A total of 26 studies was included in current META-ANALYSIS in which SA was reported in 2280 pregnant women with GDM. But in 24145 pregnant women without GDM SA occurred in 2386.Significant heterogeneity was observed between the results (P<0.001, I-square=68.3, Q=30.6).According to the findings, total odds ratio of SA among pregnant women with GDM was 3.01 times more than that in pregnant women without GDM (95% CI: 2.38–3.82).Conclusion: Appropriate control and screening for GDM in pregnant women could reduce the risk of SA.

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APA: Copy

MOOSAZADEH, MAHMOOD, BANAKAR, MORTEZA, BEHBAHANI, DARIUSH, AKBARI, MARYAM, DABBAGH MANESH, MOHAMMAD HOSEIN, MOHAMADKHANI, MINOO, & TABRIZI, REZA. (2017). ASSOCIATION BETWEEN GESTATIONAL DIABETES MELLITUS AND SPONTANEOUS ABORTION: A SYSTEMATIC REVIEW AND META-ANALYSIS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 27(155 ), 187-195. SID. https://sid.ir/paper/45507/en

Vancouver: Copy

MOOSAZADEH MAHMOOD, BANAKAR MORTEZA, BEHBAHANI DARIUSH, AKBARI MARYAM, DABBAGH MANESH MOHAMMAD HOSEIN, MOHAMADKHANI MINOO, TABRIZI REZA. ASSOCIATION BETWEEN GESTATIONAL DIABETES MELLITUS AND SPONTANEOUS ABORTION: A SYSTEMATIC REVIEW AND META-ANALYSIS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;27(155 ):187-195. Available from: https://sid.ir/paper/45507/en

IEEE: Copy

MAHMOOD MOOSAZADEH, MORTEZA BANAKAR, DARIUSH BEHBAHANI, MARYAM AKBARI, MOHAMMAD HOSEIN DABBAGH MANESH, MINOO MOHAMADKHANI, and REZA TABRIZI, “ASSOCIATION BETWEEN GESTATIONAL DIABETES MELLITUS AND SPONTANEOUS ABORTION: A SYSTEMATIC REVIEW AND META-ANALYSIS,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 155 , pp. 187–195, 2017, [Online]. Available: https://sid.ir/paper/45507/en

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