COMPARATIVE EFFICACY OF LIDOCAINE, LIDOCAINE PLUS FENTANYL AND LIDOCAINE PLUS EPINEPHRINE IN EPIDURAL ANESTHESIA

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NASERI KARIM; SHAMI SH.; MOAZAMI F.; AHSAN B.

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Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2007 | Volume:16 | Issue:56 Page(s): 68-74

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Title

COMPARATIVE EFFICACY OF LIDOCAINE, LIDOCAINE PLUS FENTANYL AND LIDOCAINE PLUS EPINEPHRINE IN EPIDURAL ANESTHESIA

Author(s)

NASERI KARIM | SHAMI SH. | MOAZAMI F. | AHSAN B. | Issue Writer Certificate

Keywords

EPIDURAL ANESTHESIAQ3

LIDOCAINE. FENTANYLQ2

EPINEPHRINEQ3

Abstract

Background and purpose: Lidocaine is an intennediate acting local anesthetic agents used very much in epidural ariesthesia and has less risk of cardiac or CNS problems compared with bupivacaine. This study evaluated the duration of motor and sensory block of EPIDURAL ANESTHESIA with lidocaine alone, lidocoine plus EPINEPHRINE and lidocaine plus fentanyl.Materials and Methods: In this double blind study 60 ASA I and 11 patients that scheduled for elective orthopedic operation were classified by block randomization in to three groups. EPIDURAL ANESTHESIA had been prescribed with 380 mg 2% lidocaine plus lml nonnal saline 0.9% for group N, 380 mg 2% Lidocaine plus 100 m/g (lml from 1/10000 solution) for group E and 380 mg 2% lidocaine plus 500 pig fentanyl for group F. The onset of sensory block and duration of motor and sensory block were recorded.Results: The mean onset time of sensory block in three groups were the same and about 8-9 minutes. The duration of complete motor block in group E (46.5 min) and F (45.3 min) were significantly higher than group N (22.5 min). The duration of sensory block in group E (117 min) was higher than group Nand F (102 min). Hypotension happened in 40%, 50% and 60% of cases and bradycardia in 10%, 25% and 30% of cases of groups N, E and F respectively.Conclusion: The results of this study showed that there were no effects on onset time of epidural sensory block with EPINEPHRINE or fentanyl as an additive to lidocaine 2% but they have glittery direct effects on the duration of motor block. However, EPINEPHRINE can increase the duration of sensory block with lidocaine in EPIDURAL ANESTHESIA.We suggest that in cases that relaxation and complete motor block is needed in EPIDURAL ANESTHESIA EPINEPHRINE or fentanyl be added to lidocaine.

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References

DETERMINATION AND COMPARISON OF THE ONSET TIME OF EPIDURAL ANESTHESIA WITH LIDOCAINE-SUFENTANIL AND LIDOCAINE-BICARBONATE

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APA: Copy

NASERI, KARIM, SHAMI, SH., MOAZAMI, F., & AHSAN, B.. (2007). COMPARATIVE EFFICACY OF LIDOCAINE, LIDOCAINE PLUS FENTANYL AND LIDOCAINE PLUS EPINEPHRINE IN EPIDURAL ANESTHESIA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 16(56), 68-74. SID. https://sid.ir/paper/45624/en

Vancouver: Copy

NASERI KARIM, SHAMI SH., MOAZAMI F., AHSAN B.. COMPARATIVE EFFICACY OF LIDOCAINE, LIDOCAINE PLUS FENTANYL AND LIDOCAINE PLUS EPINEPHRINE IN EPIDURAL ANESTHESIA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;16(56):68-74. Available from: https://sid.ir/paper/45624/en

IEEE: Copy

KARIM NASERI, SH. SHAMI, F. MOAZAMI, and B. AHSAN, “COMPARATIVE EFFICACY OF LIDOCAINE, LIDOCAINE PLUS FENTANYL AND LIDOCAINE PLUS EPINEPHRINE IN EPIDURAL ANESTHESIA,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 56, pp. 68–74, 2007, [Online]. Available: https://sid.ir/paper/45624/en

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