ANALYTICAL FORMULATION OF THERAPEUTIC FACTORS FOR CANCER TREATMENT USING ELECTRON BEAMS

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TAHMASEBI BIRGANI MOHAMAD JAVAD; TABARI JUYBARI RAHELEH; BEHROUZ MOHAMAD ALI; ARVANDI SHOLE; TAHMASEBI MARZIEH

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Journal: Journal of Mazandaran University of Medical Sciences Year:2014 | Volume:24 | Issue:114 Page(s): 180-185

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Title

ANALYTICAL FORMULATION OF THERAPEUTIC FACTORS FOR CANCER TREATMENT USING ELECTRON BEAMS

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Keywords

ELECTRON BEAMSQ2

4 GAUSSIAN FUNCTIONQ2

PERCENTAGE DEPTH DOSEQ2

THE MOST PROBABLE ENERGYQ2

PRACTICAL RANGEQ2

Abstract

Background and purpose: ELECTRON BEAMS are extensively used in superficial cancer therapy. Unlike photon therapy, PERCENTAGE DEPTH DOSE curves (PDD) do not specify a maximum point in high energy electron therapy and include a depth range. The aim of this study was to obtain PDD by an analytical formulation which can be helpful to acquire the size of treatment area and other treatment factors such as the depth of maximum dose, THE MOST PROBABLE ENERGY (Ep), PRACTICAL RANGE (Rp), and the depth which the dose reaches the peak of 50% (R50).Material and Methods: Measurements of PDD was done in radiotherapy department of Ahvaz Golestan Hospital for Siemens Primus Plus accelerator, using ionization chamber CC13 dosimeter and a water phantom for energies of 6, 9, 12, 15, 18, and 21 MeV and different field sizes at various depths. Data was analyzed using MATLAB 7.8 software.Results: The function which had the best fit to the data was selected. This function was used to calculate the, Rp and R50 points for each field size and energy. The dependence of these points to field size and energy were also obtained.Conclusion: We found that 4 GAUSSIAN FUNCTION had the best fit to the data (r2=0.99). Rapid dose reduction was observed after a relatively flat area. The curve had a sequence that was due to photon contamination. R50 and Rp points obtained for the various fields and energies by analytical function revealed that R50 depends on the field size and energy. But, Rp depends only on energy and does not depend on field size variation.

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APA: Copy

TAHMASEBI BIRGANI, MOHAMAD JAVAD, TABARI JUYBARI, RAHELEH, BEHROUZ, MOHAMAD ALI, ARVANDI, SHOLE, & TAHMASEBI, MARZIEH. (2014). ANALYTICAL FORMULATION OF THERAPEUTIC FACTORS FOR CANCER TREATMENT USING ELECTRON BEAMS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 24(114), 180-185. SID. https://sid.ir/paper/45736/en

Vancouver: Copy

TAHMASEBI BIRGANI MOHAMAD JAVAD, TABARI JUYBARI RAHELEH, BEHROUZ MOHAMAD ALI, ARVANDI SHOLE, TAHMASEBI MARZIEH. ANALYTICAL FORMULATION OF THERAPEUTIC FACTORS FOR CANCER TREATMENT USING ELECTRON BEAMS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;24(114):180-185. Available from: https://sid.ir/paper/45736/en

IEEE: Copy

MOHAMAD JAVAD TAHMASEBI BIRGANI, RAHELEH TABARI JUYBARI, MOHAMAD ALI BEHROUZ, SHOLE ARVANDI, and MARZIEH TAHMASEBI, “ANALYTICAL FORMULATION OF THERAPEUTIC FACTORS FOR CANCER TREATMENT USING ELECTRON BEAMS,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 114, pp. 180–185, 2014, [Online]. Available: https://sid.ir/paper/45736/en

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